Nature Search

Erratum: PTEN loss in the continuum of common cancers, rare syndromes and mouse models

M. Christine Hollander
Gideon M. Blumenthal
Phillip A. Dennis
Amendments and Corrections12 May 2011
Nature Reviews Cancer

Volume: 11, P: 458
Genomic instability, centrosome amplification, cell cycle checkpoints and Gadd45a

M Christine Hollander
Albert J Fornace Jr
Reviews09 Sept 2002
Oncogene

Volume: 21, P: 6228-6233
Gadd45a regulates β-catenin distribution and maintains cell–cell adhesion/contact

J Ji
R Liu
Q Zhan
Research23 Apr 2007
Oncogene

Volume: 26, P: 6396-6405
Gadd34 functional domains involved in growth suppression and apoptosis

M Christine Hollander
Silpa Poola-Kella
Albert J Fornace Jr
Research17 Jun 2003
Oncogene

Volume: 22, P: 3827-3832
Inhibitory effect of Bcl-2 on p53-mediated transactivation following genotoxic stress

Qimin Zhan
Udo Kontny
Albert J Fornace Jr
Research20 Jan 1999
Oncogene

Volume: 18, P: 297-304
Apoptosis-induced nuclear expulsion in tumor cells drives S100a4-mediated metastatic outgrowth through the RAGE pathway

Park et al. show that in the process of metastasis, dying tumor cells enhance the outgrowth of their surviving counterparts via nuclear expulsion, resulting in an extracellular DNA–protein complex that activates RAGE receptors on tumor cells.

Woo-Yong Park
Justin M. Gray
Li Yang
ResearchOpen Access27 Mar 2023
Nature Cancer

Volume: 4, P: 419-435
Genome-wide association analyses identify distinct genetic architectures for age-related macular degeneration across ancestries

Multi-ancestry genome-wide analyses identify new risk loci for age-related macular degeneration. Ancestry-specific analyses identify distinct effects at major risk loci, including smaller effect sizes for CFH risk alleles in haplotypes of African ancestry.

Bryan R. Gorman
Georgios Voloudakis
Sudha K. Iyengar
Research02 Dec 2024
Nature Genetics

Volume: 56, P: 2659-2671
Genomic instability in Gadd45a-deficient mice

M. Christine Hollander
M. Saeed Sheikh
Albert J. Fornace Jr
Research01 Oct 1999
Nature Genetics

Volume: 23, P: 176-184
miR-130a and miR-145 reprogram Gr-1⁺CD11b⁺ myeloid cells and inhibit tumor metastasis through improved host immunity

Tumours produce soluble factors that contribute to the expansion of Gr-1⁺CD11b⁺ immature myeloid cells with TGFβ dependent immune suppressive function. Here, the authors show miR-130a and miR-145 target TβRII and reprogram these cells by altering the cytokine microenvironment, improving anti-tumour immunity and inhibiting metastasis in preclinical mouse models.

Hiroki Ishii
Suman K. Vodnala
Li Yang
ResearchOpen Access04 Jul 2018
Nature Communications

Volume: 9, P: 1-15
A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants

Iris Heid, Gonçalo Abecasis, Sudha Iyengar and colleagues report the results of a large genome-wide association meta-analysis of macular degeneration based on over 43,000 subjects. They identify 16 new risk loci, including some very rare coding variants.

Lars G Fritsche
Wilmar Igl
Iris M Heid
Research21 Dec 2015
Nature Genetics

Volume: 48, P: 134-143
Base excision DNA repair defect in Gadd45a-deficient cells

H J Jung
E H Kim
Y R Seo
Research18 Jun 2007
Oncogene

Volume: 26, P: 7517-7525
Genome-wide association study identifies five new susceptibility loci for primary angle closure glaucoma

Chiea Chuen Khor, Tin Aung and colleagues report the results of a large genome-wide association study of primary angle closure glaucoma. They identify five new susceptibility loci and provide insights into disease pathogenesis.

Chiea Chuen Khor
Tan Do
Tin Aung
Research04 Apr 2016
Nature Genetics

Volume: 48, P: 556-562
PTEN loss in the continuum of common cancers, rare syndromes and mouse models

PTENis one of the most frequently inactivated tumour suppressor genes in cancer, and approximately 80% of patients with Cowden syndrome have mutations inPTEN. This Review discusses the different types of PTEN-mutant tumours that occur in Cowden syndrome and the mouse models that have been engineered to study them.

M. Christine Hollander
Gideon M. Blumenthal
Phillip A. Dennis
Reviews24 Mar 2011
Nature Reviews Cancer

Volume: 11, P: 289-301
T cell and antibody responses induced by a single dose of ChAdOx1 nCoV-19 (AZD1222) vaccine in a phase 1/2 clinical trial

A single dose of the ChAdOx1 nCoV-19 vaccine elicits antibodies and cytokine-producing T cells that might help control or prevent SARS-CoV-2 infection.

Katie J. Ewer
Jordan R. Barrett
Elizabeth Stafford
Research17 Dec 2020
Nature Medicine

Volume: 27, P: 270-278
A transcriptome-wide association study based on 27 tissues identifies 106 genes potentially relevant for disease pathology in age-related macular degeneration

Tobias Strunz
Susette Lauwen
Bernhard H. F. Weber
ResearchOpen Access31 Jan 2020
Scientific Reports

Volume: 10, P: 1-16

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Erratum: PTEN loss in the continuum of common cancers, rare syndromes and mouse models

Genomic instability, centrosome amplification, cell cycle checkpoints and Gadd45a

Gadd45a regulates β-catenin distribution and maintains cell–cell adhesion/contact

Gadd34 functional domains involved in growth suppression and apoptosis

Inhibitory effect of Bcl-2 on p53-mediated transactivation following genotoxic stress

Apoptosis-induced nuclear expulsion in tumor cells drives S100a4-mediated metastatic outgrowth through the RAGE pathway

Genome-wide association analyses identify distinct genetic architectures for age-related macular degeneration across ancestries

Genomic instability in Gadd45a-deficient mice

miR-130a and miR-145 reprogram Gr-1⁺CD11b⁺ myeloid cells and inhibit tumor metastasis through improved host immunity

A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants

Base excision DNA repair defect in Gadd45a-deficient cells

Genome-wide association study identifies five new susceptibility loci for primary angle closure glaucoma

PTEN loss in the continuum of common cancers, rare syndromes and mouse models

T cell and antibody responses induced by a single dose of ChAdOx1 nCoV-19 (AZD1222) vaccine in a phase 1/2 clinical trial

A transcriptome-wide association study based on 27 tissues identifies 106 genes potentially relevant for disease pathology in age-related macular degeneration

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