The spectrally resolved fluorescence of a zinc–porphyrin dimer is used to quantify intracellular viscosity. The porphyrin dimer also acts as a singlet-oxygen sensitizer, and enables real-time observation of a surprisingly large increase in intracellular viscosity that occurs on singlet-oxygen-mediated photoinduced cell death.
- Marina K. Kuimova
- Stanley W. Botchway
- Peter R. Ogilby