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Showing 151–200 of 331 results

Advanced filters: Author: MICHAEL SILVERMAN Clear advanced filters

Myc determines the functional age state of oligodendrocyte progenitor cells

Transient expression of the pluripotency factors Oct4, Sox2, Klf4 and c-Myc can mitigate the effects of stem cell aging on tissue health. Neumann and colleagues show that Myc expression alone converts aged oligodendrocyte progenitor cells into neonatal-like cells, and is sufficient to enhance central nervous system regeneration in an otherwise aged environment.

Björn Neumann
Michael Segel
Robin J. M. Franklin
Research14 Sept 2021
Nature Aging

Volume: 1, P: 826-837
Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries

Nick Shrine
Anna L. Guyatt
Louise V. Wain
Amendments and Corrections19 Apr 2024
Nature Genetics

Volume: 56, P: 1032-1033
CROSS SECTIONAL ECHOCARDIOGRAPHY IN CONGENITAL HEART DISEASE WITH A PHASED ARRAY 80° SECTOR SCANNER

Claude Roge
Charles Kleinman
Michael A Heymann
Research01 Apr 1977
Pediatric Research

Volume: 11, P: 399
404 ZINC-BINDING LIGANDS IN DUODENAL JUICE AND SALIVA FROM NORMAL ADULTS AND ACRODERMATITIS ENTEROPATHICA PATIENTS

Clare E Casey
K Michael Hambidge
Arnold Silverman
Research01 Apr 1978
Pediatric Research

Volume: 12, P: 431
160 THE DETECTION OF VENTRICULAR SEPTAL ANEURYSM BY TWO-DIMENSIONAL ECHOCARDIOGRAPHY

Rebecca Snider
Norman H Silverman
Michael A Heymann
Research01 Apr 1978
Pediatric Research

Volume: 12, P: 390
Ultrasensitive detection of nucleic acids using deformed graphene channel field effect biosensors

Field effect transistors based on graphene hold promise for sensing applications. Here, the authors report a millimeter-sized transistor based on deformed graphene as a biosensor that can detect nucleic acid molecules having detection limit of ~18 molecules of DNA in physiological buffer solution and ~600 molecules in human serum.

Michael Taeyoung Hwang
Mohammad Heiranian
Rashid Bashir
ResearchOpen Access24 Mar 2020
Nature Communications

Volume: 11, P: 1-11
Down's syndrome and Alzheimer's disease: towards secondary prevention

A public–private partnership to establish biomarkers of dementia in Down's syndrome could aid the development of preventive therapies for the dementia associated with both Down's syndrome and Alzheimer's disease, based on the apparent common role of amyloid precursor protein in the two conditions.

Seth Ness
Michael Rafii
Husseini Manji
Comments & Opinion31 Aug 2012
Nature Reviews Drug Discovery

Volume: 11, P: 655-656
Electrically conductive Langmuir–Blodgett films of charge-transfer materials

Martin R. Bryce
Michael C. Petty
Reviews27 Apr 1995
Nature

Volume: 374, P: 771-776
Rapid construction of a whole-genome transposon insertion collection for Shewanella oneidensis by Knockout Sudoku

Knockout collections provide a valuable tool to explore gene function, yet are expensive and technically challenging to produce at a genome-wide scale. Here Baym et al. devise a cost-effective transposon-based method to quickly develop a knockout collection for the electroactive microbe Shewanella oneidensis.

Michael Baym
Lev Shaket
Buz Barstow
ResearchOpen Access10 Nov 2016
Nature Communications

Volume: 7, P: 1-13
Author Correction: Fecal microbiota transplantation plus anti-PD-1 immunotherapy in advanced melanoma: a phase I trial

Bertrand Routy
John G. Lenehan
Saman Maleki Vareki
Amendments and Corrections03 Nov 2023
Nature Medicine

Volume: 30, P: 604
Safety and feasibility of outpatient autologous stem cell transplantation in pediatric patients with primary central nervous system tumors

Jane Koo
Stacy Silverman
Jean M. Mulcahy Levy
ResearchOpen Access19 Feb 2019
Bone Marrow Transplantation

Volume: 54, P: 1605-1613
Author Correction: Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk

Nick Shrine
Abril G. Izquierdo
Martin D. Tobin
Amendments and CorrectionsOpen Access25 Sept 2023
Nature Genetics

Volume: 55, P: 1778-1779
Genomic screening and replication using the same data set in family-based association testing

Kristel Van Steen
Matthew B McQueen
Christoph Lange
Research05 Jun 2005
Nature Genetics

Volume: 37, P: 683-691
Germline Chd8 haploinsufficiency alters brain development in mouse

Strong genetic evidence points to a significant role for heterozygous mutations to general chromatin remodeling factors, such as CHD8, in autism. Gompers et al. combine genomic, neuroanatomical and behavioral approaches to present an initial integrative picture of transcriptional mechanisms and widespread impacts of Chd8 haploinsufficiency across brain development in mice.

Andrea L Gompers
Linda Su-Feher
Alex S Nord
Research26 Jun 2017
Nature Neuroscience

Volume: 20, P: 1062-1073
Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis

Michael Cho and colleagues report a genome-wide association study of risk for chronic obstructive pulmonary disease (COPD) in a large, multi-ancestry cohort. They identify 22 genome-wide significant loci, including 13 not previously associated with COPD and 4 not previously associated with any lung function trait.

Brian D Hobbs
Kim de Jong
Michael H Cho
Research06 Feb 2017
Nature Genetics

Volume: 49, P: 426-432
Pulmonary Ureaplasma urealyticum Is Associated with the Development of Acute Lung Inflammation and Chronic Lung Disease in Preterm Infants

Sailesh Kotecha
Rachel Hodge
William D Grant
Research01 Jan 2004
Pediatric Research

Volume: 55, P: 61-68
Interleukin 18 receptor 1 gene polymorphisms are associated with asthma

Guohua Zhu
Moira K B Whyte
Sreekumar G Pillai
Research02 Apr 2008
European Journal of Human Genetics

Volume: 16, P: 1083-1090
Topologically associating domains are stable units of replication-timing regulation

A study of DNA replication timing in mouse and human cells reveals that replication domains (domains of the genome which replicate at the same time) share a correlation with topologically associating domains; these results reconcile cell-type-specific sub-nuclear compartmentalization with developmentally stable chromosome domains and offer a unified model for large scale chromosome structure and function.

Benjamin D. Pope
Tyrone Ryba
David M. Gilbert
ResearchOpen Access19 Nov 2014
Nature

Volume: 515, P: 402-405
Author Correction: A genomic mutational constraint map using variation in 76,156 human genomes

Siwei Chen
Laurent C. Francioli
Konrad J. Karczewski
Amendments and Corrections15 Jan 2024
Nature

Volume: 626, P: E1
Author Correction: Inherited causes of clonal haematopoiesis in 97,691 whole genomes

Alexander G. Bick
Joshua S. Weinstock
Pradeep Natarajan
Amendments and Corrections11 Mar 2021
Nature

Volume: 591, P: E27
The solution structure of the first KH domain of FMR1, the protein responsible for the fragile X syndrome

The structure and dynamics of the first KH domain of FMR1 — the protein responsible for fragile X syndrome — reveal that an exposed loop is highly flexible despite containing a GxxG motif that is well conserved throughout the KH family. We suggest that this region provides a putative binding surface for RNA recognition.

Giovanna Musco
Abdelhakim Kharrat
Annalisa Pastore
Correspondence01 Sept 1997
Nature Structural Biology

Volume: 4, P: 712-716
Reply to: Concerns about estimating relative risk of death associated with convalescent plasma for COVID-19

Philippe Bégin
Jeannie Callum
Donald M. Arnold
Research10 Jan 2022
Nature Medicine

Volume: 28, P: 53-58
Mapping autism risk loci using genetic linkage and chromosomal rearrangements

Peter Szatmari
Andrew D Paterson
Andy Shih
Research18 Feb 2007
Nature Genetics

Volume: 39, P: 319-328
Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer

Rachael Stolzenberg-Solomon, Laufey Amundadottir and colleagues report a genome-wide association study of pancreatic cancer. They identify four new susceptibility loci.

Brian M Wolpin
Cosmeri Rizzato
Laufey T Amundadottir
Research01 Sept 2014
Nature Genetics

Volume: 46, P: 994-1000
A protein risk score for all-cause and respiratory-specific mortality in non-Hispanic white and African American individuals who smoke

Matthew Moll
Katherine A. Pratte
Michael H. Cho
ResearchOpen Access04 Sept 2024
Scientific Reports

Volume: 14, P: 1-9
Author Correction: A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response

Yang Luo
Masahiro Kanai
Soumya Raychaudhuri
Amendments and Corrections02 Nov 2021
Nature Genetics

Volume: 53, P: 1722
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

Naomi Wray and colleagues report an analysis of genome-wide association data sets from the Psychiatric Genomics Consortium for five psychiatric disorders. They find that common variation explains 17–29% of the variance in liability and provide further support for a shared genetic etiology for these related psychiatric disorders.

S Hong Lee
Stephan Ripke
Naomi R Wray
Research11 Aug 2013
Nature Genetics

Volume: 45, P: 984-994
Early Sri Lankan coastal site tracks technological change and estuarine resource exploitation over the last ca. 25,000 years

Noel Amano
Patrick Faulkner
Nicole Boivin
ResearchOpen Access04 Nov 2024
Scientific Reports

Volume: 14, P: 1-16
EVALUATION OF ARRHYTHMIAS IN CHILDREN. EXERCISE TESTING VS. AMBULATORY MONITORING

John J Rozanski
Joel Kupersmith
Kurt Hirschhorn
Research01 Apr 1977
Pediatric Research

Volume: 11, P: 399
1745 THE HYPERCARBIC VENTILATORY RESPONSE TEST: NEAR-MISS SIDS SIBLINGS OF SIDS, AND SUBSEQUENT APNEA

Michael Coleman
Christine A Reardon
Stephen J Boros
Research01 Apr 1985
Pediatric Research

Volume: 19, P: 401
DETECTION OP ARRHYTHMIAS IN CHILDHOOD: USE OP TREAD-MILL AND DYNAMIC ECG

Albert Rocchini
Michael Froed
Amnon Posenthal
Research01 Apr 1977
Pediatric Research

Volume: 11, P: 399
Publisher Correction: Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries

Seyedeh M. Zekavat
Sanni Ruotsalainen
Sebastian Zoellner
Amendments and CorrectionsOpen Access23 Aug 2018
Nature Communications

Volume: 9, P: 1-3
A Review: Newer, Noninvasive Cardiac Diagnostic Methods

William F Friedman
David J Sahn
Michael J Hirscklau
Research01 Mar 1977
Pediatric Research

Volume: 11, P: 190-197
Publisher Correction: Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries

Seyedeh M. Zekavat
Sanni Ruotsalainen
Sebastian Zoellner
Amendments and CorrectionsOpen Access01 Apr 2020
Nature Communications

Volume: 11, P: 1
POT1 loss-of-function variants predispose to familial melanoma

David Adams, Julia Newton-Bishop, Timothy Bishop, Nicholas Hayward and colleagues identify loss-of-function variants in POT1 in several families with early onset multiple primary melanoma. They further show that these variants disrupt telomere binding by POT1 and are associated with increased telomere length.

Carla Daniela Robles-Espinoza
Mark Harland
David J Adams
Research30 Mar 2014
Nature Genetics

Volume: 46, P: 478-481
Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries

Nick Shrine
Anna L. Guyatt
Louise V. Wain
Amendments and Corrections20 May 2019
Nature Genetics

Volume: 51, P: 1067
Landmarks in the evolution of prostate biopsy

Since its inception in 1922, prostate biopsy has undergone considerable changes in both technique and indication. In this Perspective, the authors describe the history of prostate biopsy and consider the role of imaging in prostate biopsy, now and in the future.

Martin J. Connor
Michael A. Gorin
Hashim U. Ahmed
Reviews18 Jan 2023
Nature Reviews Urology

Volume: 20, P: 241-258
Shifts in Arctic vegetation and associated feedbacks under climate change

This study shows that climate change could lead to a major redistribution of vegetation across the Arctic, with important implications for biosphere–atmosphere interactions, as well as for biodiversity conservation and ecosystem services. Woody vegetation is predicted to expand substantially over coming decades, causing more Arctic warming through positive climate feedbacks than previously thought.

Richard G. Pearson
Steven J. Phillips
Scott J. Goetz
Research31 Mar 2013
Nature Climate Change

Volume: 3, P: 673-677
MULLERIAN INHIBITING SUBSTANCE (MIS) DETERMINATION IN THE EVALUATION OF NONPALPABLE GONADS. • 534

Mary M Lee
Michael L Gustafson
David T MacLaughlin
Research01 Apr 1996
Pediatric Research

Volume: 39, P: 92
Transplantation of Unrelated Placental/Umbilical Cord Blood Cells for Leukocyte Adhesion Deficiency

Kirsten J Silverman
Carla M West
Andrew M Yeager
Research01 Apr 1999
Pediatric Research

Volume: 45, P: 153
Fetoplacental Blood Flow Predicts Outcome After Open Fetal Surgery for Diaphragmatic Hernia in Human Fetuses † 121

Thomas Kohl
Doff B McElhinney
Norman H Silverman
Research01 Apr 1998
Pediatric Research

Volume: 43, P: 23
Fetal and Neonatal Manifestations in a Murine Model of Congenital Heart Block, Including Fetal Echocardiographic Assessment

Michael F Lee-Poy
Shufang Zhao
Robert M Hamilton
Research01 Apr 1999
Pediatric Research

Volume: 45, P: 26
Immune and genomic correlates of response to anti-PD-1 immunotherapy in glioblastoma

Genomic, transcriptomic, and microenvironmental analyses of samples from patients with glioblastoma treated with nivolumab or pembrolizumab identifies features associated with treatment response that may help in refining patient stratification.

Junfei Zhao
Andrew X. Chen
Raul Rabadan
Research11 Feb 2019
Nature Medicine

Volume: 25, P: 462-469
Prefrontal white matter volume is disproportionately larger in humans than in other primates

P Thomas Schoenemann
Michael J Sheehan
L Daniel Glotzer
Research23 Jan 2005
Nature Neuroscience

Volume: 8, P: 242-252
JNK/SAPK activity contributes to TRAIL-induced apoptosis

Ingrid Herr
Dagmar Wilhelm
Klaus-Michael Debatin
Research28 Jan 1999
Cell Death & Differentiation

Volume: 6, P: 130-135
Association of IL8, CXCR2 and TNF-α polymorphisms and airway disease

Melanie C. Matheson
Justine A. Ellis
Michael J. Abramson
Research01 Mar 2006
Journal of Human Genetics

Volume: 51, P: 196-203
Developmental Factors Contributing to the Susceptibility to Bradycardia in Isolated, Cultured Fetal Mouse Hearts

Michael Maurer Jr.
Research01 Sept 1979
Pediatric Research

Volume: 13, P: 1052-1057
Ontogeny of Surfactant Proteins A and B in Human Amniotic Fluid as Indices of Fetal Lung Maturity

Gloria S Pryhuber
William M Hull
Jeffrey A Whitsett
Research01 Dec 1991
Pediatric Research

Volume: 30, P: 597-605
Ontogeny of the Immune System: Fetal Lamb as a Model

Rukmani Raghunathan
Michael E Miller
Judy Faust
Research01 May 1984
Pediatric Research

Volume: 18, P: 451-456
Author Correction: FAM222A encodes a protein which accumulates in plaques in Alzheimer’s disease

Tingxiang Yan
Jingjing Liang
Xinglong Wang
Amendments and CorrectionsOpen Access11 Jul 2022
Nature Communications

Volume: 13, P: 1-2

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