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Advanced filters: Author: Maanasa Raghavan Clear advanced filters

  • In this Journal Club, Maanasa Raghavan recalls a 1984 paper by Higuchi et al. that demonstrated how sequencing ancient DNA provides unique evolutionary insights.

    • Maanasa Raghavan
    Research Highlights
    Nature Reviews Genetics
    Volume: 26, P: 297

  • The first genome sequence of an ancient human is reported. It comes from an approximately 4,000-year-old permafrost-preserved hair from a male from the first known culture to settle in Greenland. Functional single-nucleotide polymorphism (SNP) assessment is used to assign possible phenotypic characteristics and high-confidence SNPs are compared to those of contemporary populations to find those most closely related to the individual.

    • Morten Rasmussen
    • Yingrui Li
    • Eske Willerslev
    ResearchOpen Access
    Nature
    Volume: 463, P: 757-762

  • Draft genomes of two south-central Siberian individuals dating to 24,000 and 17,000 years ago show that they are genetically closely related to modern-day western Eurasians and Native Americans but not to east Asians; the results have implications for our understanding of the origins of Native Americans.

    • Maanasa Raghavan
    • Pontus Skoglund
    • Eske Willerslev
    Research
    Nature
    Volume: 505, P: 87-91

  • Our current understanding of the demographic history of Greenland relies on preserved fossils. Here, the authors sequence ancient DNA from four midden deposits and find a prominent role for caribou, walrus and whale species in Paleo-Inuit cultures not evident from the fossil record.

    • Frederik Valeur Seersholm
    • Mikkel Winther Pedersen
    • Anders Johannes Hansen
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-9