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Showing 1–3 of 3 results
Advanced filters: Author: Machteld M. Tiemessen Clear advanced filters

  • The authors report an efficacious vaccine for human metapneumovirus based on a prefusion-stabilized fusion protein trimer that does not require a trimerization domain, designed using an AI convolutional classifier trained to predict optimized complex polar interactions.

    • Mark J. G. Bakkers
    • Tina Ritschel
    • Johannes P. M. Langedijk
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-17

  • This Review covers the recently discovered roles of WNT proteins in the regulation of haematopoietic stem-cell fate, T- and B-cell development and activation, and dendritic-cell maturation. These new immunohaematological functions of WNT proteins have implications for the development of haematological malignancies.

    • Frank J. T. Staal
    • Tiago C. Luis
    • Machteld M. Tiemessen
    Reviews
    Nature Reviews Immunology
    Volume: 8, P: 581-593