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Showing 1–2 of 2 results
Advanced filters: Author: Maciej Glyda Clear advanced filters
  • The molecular mechanisms that underlie associations in GWAS, incl. chronic kidney disease (CKD), are largely unknown. Here, the authors perform an integrative analysis of genetic, transcriptomic and epigenomic data from human kidney to pinpoint plausible molecular pathways of CKD genetic associations.

    • Xiaoguang Xu
    • James M. Eales
    • Maciej Tomaszewski
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-12
  • Gene expression, alternative splicing and DNA methylation profiles from human kidney samples provide insights into the effects of common variants influencing blood pressure. Mendelian randomization uncovers the effects of blood pressure on renal outcomes.

    • James M. Eales
    • Xiao Jiang
    • Maciej Tomaszewski
    Research
    Nature Genetics
    Volume: 53, P: 630-637