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Advanced filters: Author: Madhusudhan Budatha Clear advanced filters

  • Using a chimaeric integrin α5 (where the tail is replaced by that of α2), Yun et al. show that in endothelial cells, integrin α5 interacts with the cAMP-specific phosphodiesterase PDE4D5 to reduce cAMP levels and inflammation both in vitro and in vivo.

    • Sanguk Yun
    • Madhusudhan Budatha
    • Martin A. Schwartz
    Research
    Nature Cell Biology
    Volume: 18, P: 1043-1053