Nature Search

Crystals competing for space

Analysis of the growth patterns of calcitic prisms within the shell of the fan mollusc Pinna nobilis shows that growth can be predicted using grain theory and that the organic casings of the prisms set the thermodynamic boundaries.

Nico A. J. M. Sommerdijk
Maggie Cusack
News & Views20 Nov 2014
Nature Materials

Volume: 13, P: 1078-1079
GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

An analysis of 24,202 critical cases of COVID-19 identifies potentially druggable targets in inflammatory signalling (JAK1), monocyte–macrophage activation and endothelial permeability (PDE4A), immunometabolism (SLC2A5 and AK5), and host factors required for viral entry and replication (TMPRSS2 and RAB2A).

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
ResearchOpen Access17 May 2023
Nature

Volume: 617, P: 764-768
Biomineral shell formation under ocean acidification: a shift from order to chaos

Susan C. Fitzer
Peter Chung
Maggie Cusack
ResearchOpen Access15 Feb 2016
Scientific Reports

Volume: 6, P: 1-7
Ocean acidification impacts mussel control on biomineralisation

Susan C. Fitzer
Vernon R. Phoenix
Nicholas A. Kamenos
ResearchOpen Access28 Aug 2014
Scientific Reports

Volume: 4, P: 1-7
Mechanical adaptation of brachiopod shells via hydration-induced structural changes

Bioinspired materials require an understanding of how biomaterials achieve the materials properties. Here, the authors report on the load-bearing shell of Discinisca tenuis and explore how hydration changes the dry shell from hard and stiff to soft and flexible within minutes by reorganisation caused by organic matrix swelling.

Johannes Ihli
Anna S. Schenk
Fabio Nudelman
ResearchOpen Access10 Sept 2021
Nature Communications

Volume: 12, P: 1-12
Mapping the human genetic architecture of COVID-19

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Mari E. K. Niemi
Juha Karjalainen
Chloe Donohue
ResearchOpen Access08 Jul 2021
Nature

Volume: 600, P: 472-477
Age-related delay in visual and auditory evoked responses is mediated by white- and grey-matter differences

Neural processing speed slows with age, but the relationship between this slowing and brain atrophy is unknown. Here, authors show that age-related functional brain differences in auditory and visual processing are partly due to structural differences in the distinct brain regions underlying these processes.

D. Price
L. K. Tyler
R. N. A. Henson
ResearchOpen Access09 Jun 2017
Nature Communications

Volume: 8, P: 1-12
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
Red coralline algae assessed as marine pH proxies using ¹¹B MAS NMR

M. Cusack
N. A. Kamenos
G. Tricot
ResearchOpen Access02 Feb 2015
Scientific Reports

Volume: 5, P: 1-3
Whole-genome sequencing reveals host factors underlying critical COVID-19

Whole-genome sequencing, transcriptome-wide association and fine-mapping analyses in over 7,000 individuals with critical COVID-19 are used to identify 16 independent variants that are associated with severe illness in COVID-19.

Athanasios Kousathanas
Erola Pairo-Castineira
J. Kenneth Baillie
ResearchOpen Access07 Mar 2022
Nature

Volume: 607, P: 97-103
Noradrenergic-dependent functions are associated with age-related locus coeruleus signal intensity differences

Alterations of locus coeruleus signal intensity have been associated with functional changes in health and disease. Here, the authors tested a pre-registered hypothesis on a large number of subjects as part of the Cam-CAN consortium.

Kathy Y. Liu
Rogier A. Kievit
Dorothea Hämmerer
ResearchOpen Access06 Apr 2020
Nature Communications

Volume: 11, P: 1-9
Author Correction: GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
Amendments and CorrectionsOpen Access11 Jul 2023
Nature

Volume: 619, P: E61
Preserved cognitive functions with age are determined by domain-dependent shifts in network responsivity

Cognitive abilities change with age, but why some decline and some do not is not clear. Here, the authors use data from the Cam-CAN cohort to show that distributed, multi-component brain responsivity and default-mode deactivation supports and characterizes preserved cognition across the adult lifespan.

Dávid Samu
Karen L. Campbell
Lorraine K. Tyler
ResearchOpen Access08 May 2017
Nature Communications

Volume: 8, P: 1-14
Distinct aspects of frontal lobe structure mediate age-related differences in fluid intelligence and multitasking

Executive functions are affected by ageing but it is unclear how. Kievit et al.use brain imaging and modelling approaches to show how multifactorial explanations outperform single-factor models when relating age-related differences in grey and white matter to differences in fluid intelligence and multitasking.

Rogier A. Kievit
Simon W. Davis
Richard N.A. Henson
ResearchOpen Access18 Dec 2014
Nature Communications

Volume: 5, P: 1-10
Ageing increases reliance on sensorimotor prediction through structural and functional differences in frontostriatal circuits

Decline in sensorimotor skills with age may be due to an overreliance on the prediction of the sensory consequences of one’s actions. Here the authors show that sensorimotor attenuation increases with age, and that this is associated with structural and functional changes in frontostriatal circuits.

Noham Wolpe
James N. Ingram
James B. Rowe
ResearchOpen Access03 Oct 2016
Nature Communications

Volume: 7, P: 1-11
Distinct components of cardiovascular health are linked with age-related differences in cognitive abilities

Deborah L. O. King
Richard N. Henson
Kamen A. Tsvetanov
ResearchOpen Access18 Jan 2023
Scientific Reports

Volume: 13, P: 1-14
Sensory attenuation in Parkinson’s disease is related to disease severity and dopamine dose

Noham Wolpe
Jiaxiang Zhang
James B. Rowe
ResearchOpen Access23 Oct 2018
Scientific Reports

Volume: 8, P: 1-10
Perceptual and conceptual processing of visual objects across the adult lifespan

Rose Bruffaerts
Lorraine K. Tyler
Alex Clarke
ResearchOpen Access24 Sept 2019
Scientific Reports

Volume: 9, P: 1-13
Multiple determinants of lifespan memory differences

Richard N. Henson
Karen L. Campbell
Rogier A. Kievit
ResearchOpen Access07 Sept 2016
Scientific Reports

Volume: 6, P: 1-14
Publisher Correction: Sensory attenuation in Parkinson’s disease is related to disease severity and dopamine dose

Noham Wolpe
Jiaxiang Zhang
James B. Rowe
Amendments and CorrectionsOpen Access22 Nov 2018
Scientific Reports

Volume: 8, P: 1-2

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