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Showing 1–2 of 2 results
Advanced filters: Author: Maija Jäntti Clear advanced filters

  • The chromatin state origins of uterine leiomyoma (UL) remain to be explored. Here, the authors integrate data from genome-wide association studies and deep regulatory genomics data from myometrium and the three UL subclasses to understand population-level disease predisposition at chromatin state level.

    • Maritta Räisänen
    • Eevi Kaasinen
    • Lauri A. Aaltonen
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-16

  • Analyses of samples from 728 women with uterine leiomyomas (uterine fibroids), and public data, show that somatic and germline mutations in the SRCAP histone-loading complex genes are associated with the condition.

    • Davide G. Berta
    • Heli Kuisma
    • Lauri A. Aaltonen
    Research
    Nature
    Volume: 596, P: 398-403