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Oxytocinergic input from the paraventricular nucleus to the nucleus accumbens core modulates methamphetamine-conditioned place preference

The mechanisms whereby METH yields strong addiction potential is not fully understood. Here, authors show that METH may impair the function of the endogenous OXT system, particularly the PVN^OXT-NAc core pathway, suggesting OXT-based therapies for METH use disorder (MUD).

Ying-jie Cheng
Gui-ying Zan
Min Zhao
ResearchOpen Access23 May 2025
Nature Communications

Volume: 16, P: 1-13
Parabrachial nucleus circuit governs neuropathic pain-like behavior

The parabrachial nucleus (PBN) projects to the amygdala, and contributes to affective aspects of neuropathic pain. Here the authors demonstrate that the lateral parabrachial nucleus (LPBN) contributes to hypersensitivity in a mouse model of neuropathic pain.

Li Sun
Rui Liu
Shumin Duan
ResearchOpen Access25 Nov 2020
Nature Communications

Volume: 11, P: 1-21
Inhibition of Influenza A virus propagation by benzoselenoxanthenes stabilizing TMPRSS2 Gene G-quadruplex and hence down-regulating TMPRSS2 expression

Li-Wen Shen
Man-Qing Qian
Wen Zhang
ResearchOpen Access06 May 2020
Scientific Reports

Volume: 10, P: 1-12

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