Gangliosides play crucial roles in the nervous system, with aberrant metabolism linked to diseases like cancer and neurodegeneration, but tools to visualize and detect gangliosides remain limited and non-specific. Here, the authors introduce MM-JH-2, a dual fluorescent and Raman-active probe, enabling specific ganglioside labeling and differentiation between cells that differ in ganglioside biosynthetic flux.
- Mana Mohan Mukherjee
- Matthew D. Watson
- John A. Hanover
