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Showing 1–3 of 3 results
Advanced filters: Author: Manish Boolchandani Clear advanced filters
  • Environments where antibiotics are used indiscriminately exhibit microbial communities that can represent hot-spots of resistance gene enrichment, which in turn could spread to humans. Here, the authors characterize how exposure to swine farms environment lead to temporal changes in the gut microbiome and resistome of healthy veterinary students.

    • Jian Sun
    • Xiao-Ping Liao
    • Ya-Hong Liu
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-11
  • Here, the authors characterize the microbiome and resistome in a longitudinal cohort of 159 international students visiting the Andean city of Cusco, Peru. They find that international travel associates with spread of antimicrobial resistance, and that travelers’ diarrhea increases a persons’ risk for acquiring antimicrobial-resistant pathogens, while a diverse, “healthy” microbiome can be protective against diarrhea.

    • Manish Boolchandani
    • Kevin S. Blake
    • Gautam Dantas
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-19
  • Next-generation sequencing has improved the identification and characterization of antimicrobial resistance. Focusing on sequence-based discovery of antibiotic resistance genes, this Review discusses computational strategies and resources for resistance gene identification in genomic and metagenomic samples, including recent deep-learning approaches.

    • Manish Boolchandani
    • Alaric W. D’Souza
    • Gautam Dantas
    Reviews
    Nature Reviews Genetics
    Volume: 20, P: 356-370