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Showing 1–5 of 5 results
Advanced filters: Author: María Almuedo-Castillo Clear advanced filters

  • Almuedo-Castillo et al. show that extirpated embryos are reduced in size but exhibit normal proportions. Following a computational screen, the authors identify an increased concentration of the Nodal inhibitor Lefty to be responsible for the size scaling.

    • María Almuedo-Castillo
    • Alexander Bläßle
    • Patrick Müller
    Research
    Nature Cell Biology
    Volume: 20, P: 1032-1042

  • CTCF is as an architectural protein involved in 3D genome folding; however its contribution to animal development has not been well characterized. Here the authors show that CTCF is not only pivotal for 3D chromatin structure and enhancer-promoter interactions in zebrafish, but it is also essential for controlling the expression of thousands of genes during development.

    • Martin Franke
    • Elisa De la Calle-Mustienes
    • José L. Gómez-Skarmeta
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-19

  • YAP signaling has been established as a mechanotransductive pathway in multiple contexts, but its developmental roles are still being explored. Here they show that YAP signaling sustains intracellular tension to direct cell migration during embryonic axis assembly.

    • Ana Sousa-Ortega
    • Javier Vázquez-Marín
    • Juan R. Martínez-Morales
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-17

  • The gene regulatory network controlling the bifurcation of common progenitors into the neural retina and retinal-pigmented epithelium programs remains poorly understood. Here the authors study transcriptome dynamics and chromatin accessibility during this process in zebrafish, revealing network redundancy, as well as context-dependent and sequential transcription factor activity.

    • Lorena Buono
    • Jorge Corbacho
    • Juan-Ramón Martínez-Morales
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-16