Nature Search

Meta-analysis of 22,710 human microbiome metagenomes defines an oral-to-gut microbial enrichment score and associations with host health and disease

Here, the authors present an update to a widely used curatedMetagenomicData (cMD) database and use it to create a catalog of microbiome-phenotype associations (age, sex, body mass index), and develop an oral enrichment score in the gut microbiome independently of age.

Paolo Manghi
Giacomo Antonello
Levi Waldron
ResearchOpen Access23 Dec 2025
Nature Communications

Volume: 17, P: 1-13
Ultrafast adaptive optics for imaging the living human eye

Adaptive optics (AO) corrects eye aberrations for sharp imaging, but their dynamics in clinical scenarios are much higher than expected. Ultrafast AO improves aberration correction and retinal imaging performance in these cases.

Yan Liu
James A. Crowell
Donald T. Miller
ResearchOpen Access29 Nov 2024
Nature Communications

Volume: 15, P: 1-17
Correction: Corrigendum: SMN2 splice modulators enhance U1–pre-mRNA association and rescue SMA mice

James Palacino
Susanne E Swalley
Rajeev Sivasankaran
Amendments and Corrections18 Mar 2016
Nature Chemical Biology

Volume: 12, P: 304
Correction: Corrigendum: SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice

James Palacino
Susanne E Swalley
Rajeev Sivasankaran
Amendments and Corrections18 Aug 2015
Nature Chemical Biology

Volume: 11, P: 741
Phylogeography of the second plague pandemic revealed through analysis of historical Yersinia pestis genomes

The second plague pandemic, caused by Yersinia pestis, started in the 14th century and recurred in Europe until the 18th century. Here, the authors reconstruct ancient Y. pestis genomes from human remains spanning this period, shedding light into the phylogeography and population structure of the European strains.

Maria A. Spyrou
Marcel Keller
Johannes Krause
ResearchOpen Access02 Oct 2019
Nature Communications

Volume: 10, P: 1-13
The origins and spread of domestic horses from the Western Eurasian steppes

Analysis of 273 ancient horse genomes reveals that modern domestic horses originated in the Western Eurasian steppes, especially the lower Volga-Don region.

Pablo Librado
Naveed Khan
Ludovic Orlando
ResearchOpen Access20 Oct 2021
Nature

Volume: 598, P: 634-640
MINSTED nanoscopy enters the Ångström localization range

Sub-nanometer localization precision is achieved with all-optical microscopy.

Michael Weber
Henrik von der Emde
Stefan W. Hell
ResearchOpen Access07 Nov 2022
Nature Biotechnology

Volume: 41, P: 569-576
Lethal Borna disease virus 1 infections of humans and animals – in-depth molecular epidemiology and phylogeography

Borna disease virus 1 (BoDV-1) is a zoonotic pathogen endemic in bicoloured white-toothed shrews in Central Europe that can cause fatal encephalitis in humans and other mammals. Here, the authors investigate the molecular epidemiology and phylogeography of BoDV-1 using newly collected and archived samples.

Arnt Ebinger
Pauline D. Santos
Dennis Rubbenstroth
ResearchOpen Access10 Sept 2024
Nature Communications

Volume: 15, P: 1-16
MINSTED fluorescence localization and nanoscopy

A stimulated-emission-depletion-based fluorescence localization and super-resolution microscopy concept that is capable of attaining a spatial resolution down at the size scale of the fluorophores themselves and a localization precision of 1–3 nm in standard deviation is reported.

Michael Weber
Marcel Leutenegger
Stefan W. Hell
ResearchOpen Access15 Mar 2021
Nature Photonics

Volume: 15, P: 361-366
SMN2 splice modulators enhance U1–pre-mRNA association and rescue SMA mice

A high-throughput screen identified a small molecule that promoted inclusion of SMN2 exon 7, increased SMN2 protein levels and extended survival in a SMA mouse model through stabilization of the interaction between SMN2 pre-mRNA and U1 snRNP complex.

James Palacino
Susanne E Swalley
Rajeev Sivasankaran
Research01 Jun 2015
Nature Chemical Biology

Volume: 11, P: 511-517
Wnt glycoproteins regulate the expression of FoxN1, the gene defective in nude mice

Gina Balciunaite
Marcel P. Keller
Georg A. Holländer
Research15 Oct 2002
Nature Immunology

Volume: 3, P: 1102-1108
Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept

The authors defined a roadmap for investigating the genetic covariance between structural or functional brain phenotypes and risk for psychiatric disorders. Their proof-of-concept study using the largest available common variant data sets for schizophrenia and volumes of several (mainly subcortical) brain structures did not find evidence of genetic overlap.

Barbara Franke
Jason L Stein
Patrick F Sullivan
Research01 Feb 2016
Nature Neuroscience

Volume: 19, P: 420-431
CRISPR/Cas9 mediated targeted knock-in of eglA gene to improve endoglucanase activity of Aspergillus fumigatus LMB-35Aa

J. S. Benites-Pariente
I. Samolski
G. K. Villena
ResearchOpen Access23 Aug 2024
Scientific Reports

Volume: 14, P: 1-12
Microbial network disturbances in relapsing refractory Crohn’s disease

A disturbed microbial network characterizes relapsing refractory Crohn’s disease and antedates disease recurrence after surgical removal of the active disease segment.

Bahtiyar Yilmaz
Pascal Juillerat
Andrew J. Macpherson
Research21 Jan 2019
Nature Medicine

Volume: 25, P: 323-336
Under-ice environment observations from a remotely operated vehicle during the MOSAiC expedition

Philipp Anhaus
Christian Katlein
Marcel Nicolaus
ResearchOpen Access05 Jun 2025
Scientific Data

Volume: 12, P: 1-24
Polyandry and non-random fertilisation maintain long-term genetic diversity in an isolated island population of adders (Vipera berus)

Thomas Madsen
Beata Ujvari
Marcel Klaassen
Research06 Dec 2022
Heredity

Volume: 130, P: 64-72
Agricultural intensification reduces microbial network complexity and the abundance of keystone taxa in roots

Samiran Banerjee
Florian Walder
Marcel G. A. van der Heijden
ResearchOpen Access08 Mar 2019
The ISME Journal

Volume: 13, P: 1722-1736
Foxn1 regulates key target genes essential for T cell development in postnatal thymic epithelial cells

Holländer and colleagues provide a map of genes that are direct targets of the transcription factor Foxn1 in thymic epithelial cells and show that Foxn1 controls genes encoding products involved in thymocyte development, antigen processing and thymocyte selection.

Saulius Žuklys
Adam Handel
Georg A Holländer
Research22 Aug 2016
Nature Immunology

Volume: 17, P: 1206-1215
Proteomics as a new tool to study fingermark ageing in forensics

Stijn Oonk
Tom Schuurmans
Marcel de Puit
ResearchOpen Access06 Nov 2018
Scientific Reports

Volume: 8, P: 1-11
Publisher Correction: Microbial network disturbances in relapsing refractory Crohn’s disease

Bahtiyar Yilmaz
Pascal Juillerat
Andrew J. Macpherson
Amendments and Corrections07 Mar 2019
Nature Medicine

Volume: 25, P: 701
The neural and cognitive basis of expository text comprehension

Timothy A. Keller
Robert A. Mason
Marcel Adam Just
ResearchOpen Access21 Mar 2024
npj Science of Learning

Volume: 9, P: 1-12
Structural investigation of Trypanosoma cruzi Akt-like kinase as drug target against Chagas disease

Karina A. Stadler
Lesly J. Ortiz-Joya
Nina Gubensäk
ResearchOpen Access02 May 2024
Scientific Reports

Volume: 14, P: 1-23
Achromatic light patterning and improved image reconstruction for parallelized RESOLFT nanoscopy

Andriy Chmyrov
Marcel Leutenegger
Stefan W. Hell
ResearchOpen Access20 Mar 2017
Scientific Reports

Volume: 7, P: 1-9
Housing environment and mental health of Europeans during the COVID-19 pandemic: a cross-country comparison

Amélie Keller
Jonathan Groot
Tibor V. Varga
ResearchOpen Access04 Apr 2022
Scientific Reports

Volume: 12, P: 1-11
The Scales Project, a cross-national dataset on the interpretation of thermal perception scales

Marcel Schweiker
Amar Abdul-Zahra
Zahra Sadat Zomorodian
ResearchOpen Access26 Nov 2019
Scientific Data

Volume: 6, P: 1-10
Mobilise-D insights to estimate real-world walking speed in multiple conditions with a wearable device

Cameron Kirk
Arne Küderle
Linda Van Gelder
ResearchOpen Access19 Jan 2024
Scientific Reports

Volume: 14, P: 1-23
Loss of the branched-chain amino acid transporter CD98hc alters the development of colonic macrophages in mice

CD98hc in macrophages attenuates the severity of colitis. This change in the macrophage development is associated with increased expression of apoptotic genes, suggesting that CD98hc maintains the gut homeostasis by ensuring the development of gut macrophages.

Philipp Wuggenig
Berna Kaya
Jan Hendrik Niess
ResearchOpen Access18 Mar 2020
Communications Biology

Volume: 3, P: 1-19
Author Correction: Mobilise-D insights to estimate real-world walking speed in multiple conditions with a wearable device

Cameron Kirk
Arne Küderle
Linda Van Gelder
Amendments and CorrectionsOpen Access21 Nov 2024
Scientific Reports

Volume: 14, P: 1-3

Search

Meta-analysis of 22,710 human microbiome metagenomes defines an oral-to-gut microbial enrichment score and associations with host health and disease

Ultrafast adaptive optics for imaging the living human eye

Correction: Corrigendum: SMN2 splice modulators enhance U1–pre-mRNA association and rescue SMA mice

Correction: Corrigendum: SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice

Phylogeography of the second plague pandemic revealed through analysis of historical Yersinia pestis genomes

The origins and spread of domestic horses from the Western Eurasian steppes

MINSTED nanoscopy enters the Ångström localization range

Lethal Borna disease virus 1 infections of humans and animals – in-depth molecular epidemiology and phylogeography

MINSTED fluorescence localization and nanoscopy

SMN2 splice modulators enhance U1–pre-mRNA association and rescue SMA mice

Wnt glycoproteins regulate the expression of FoxN1, the gene defective in nude mice

Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept

CRISPR/Cas9 mediated targeted knock-in of eglA gene to improve endoglucanase activity of Aspergillus fumigatus LMB-35Aa

Microbial network disturbances in relapsing refractory Crohn’s disease

Under-ice environment observations from a remotely operated vehicle during the MOSAiC expedition

Polyandry and non-random fertilisation maintain long-term genetic diversity in an isolated island population of adders (Vipera berus)

Agricultural intensification reduces microbial network complexity and the abundance of keystone taxa in roots

Foxn1 regulates key target genes essential for T cell development in postnatal thymic epithelial cells

Proteomics as a new tool to study fingermark ageing in forensics

Publisher Correction: Microbial network disturbances in relapsing refractory Crohn’s disease

The neural and cognitive basis of expository text comprehension

Structural investigation of Trypanosoma cruzi Akt-like kinase as drug target against Chagas disease

Achromatic light patterning and improved image reconstruction for parallelized RESOLFT nanoscopy

Housing environment and mental health of Europeans during the COVID-19 pandemic: a cross-country comparison

The Scales Project, a cross-national dataset on the interpretation of thermal perception scales

Mobilise-D insights to estimate real-world walking speed in multiple conditions with a wearable device

Loss of the branched-chain amino acid transporter CD98hc alters the development of colonic macrophages in mice

Author Correction: Mobilise-D insights to estimate real-world walking speed in multiple conditions with a wearable device

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