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Genome-wide copy number variation study associates metabotropic glutamate receptor gene networks with attention deficit hyperactivity disorder

Hakon Hakonarson and colleagues report a genome-wide copy number variation study in 3,506 cases of attention-deficit hyperactivity disorder. The authors identify a statistically significant enrichment of CNVs impacting metabotropic glutamate receptor genes.

Josephine Elia
Joseph T Glessner
Hakon Hakonarson
Research04 Dec 2011
Nature Genetics

Volume: 44, P: 78-84
Newly identified genetic risk variants for celiac disease related to the immune response

Karen A Hunt
Alexandra Zhernakova
David A van Heel
Research02 Mar 2008
Nature Genetics

Volume: 40, P: 395-402
Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

A genome-wide association study for attention deficit/hyperactivity disorder (ADHD) identifies 12 loci and implicates neurodevelopmental pathways and conserved regions of the genome as being involved in underlying ADHD biology.

Ditte Demontis
Raymond K. Walters
Benjamin M. Neale
Research26 Nov 2018
Nature Genetics

Volume: 51, P: 63-75
Functional Impact of An ADHD-Associated DIRAS2 Promoter Polymorphism

Lena Grünewald
Elisabeth Toverud Landaas
Andreas Reif
Research01 Jul 2016
Neuropsychopharmacology

Volume: 41, P: 3025-3031
DIRAS2 is Associated with Adult ADHD, Related Traits, and Co-Morbid Disorders

Andreas Reif
T Trang Nguyen
Klaus-Peter Lesch
Research13 Jul 2011
Neuropsychopharmacology

Volume: 36, P: 2318-2327
Orexin in the anxiety spectrum: association of a HCRTR1 polymorphism with panic disorder/agoraphobia, CBT treatment response and fear-related intermediate phenotypes

Michael G. Gottschalk
Jan Richter
Katharina Domschke
ResearchOpen Access04 Feb 2019
Translational Psychiatry

Volume: 9, P: 1-13
Erratum: DIRAS2 is Associated with Adult ADHD, Related Traits, and Co-Morbid Disorders

Andreas Reif
T Trang Nguyen
Helmut Schäfer
Amendments and Corrections13 Feb 2012
Neuropsychopharmacology

Volume: 37, P: 1076
Increased locomotor activity via regulation of GABAergic signalling in foxp2 mutant zebrafish—implications for neurodevelopmental disorders

Teresa M. Lüffe
Andrea D’Orazio
Christina Lillesaar
ResearchOpen Access14 Oct 2021
Translational Psychiatry

Volume: 11, P: 1-12
Identification of ADHD risk genes in extended pedigrees by combining linkage analysis and whole-exome sequencing

Jordi Corominas
Marieke Klein
Klaus-Peter Lesch
ResearchOpen Access16 Aug 2018
Molecular Psychiatry

Volume: 25, P: 2047-2057

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Genome-wide copy number variation study associates metabotropic glutamate receptor gene networks with attention deficit hyperactivity disorder

Newly identified genetic risk variants for celiac disease related to the immune response

Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

Functional Impact of An ADHD-Associated DIRAS2 Promoter Polymorphism

DIRAS2 is Associated with Adult ADHD, Related Traits, and Co-Morbid Disorders

Orexin in the anxiety spectrum: association of a HCRTR1 polymorphism with panic disorder/agoraphobia, CBT treatment response and fear-related intermediate phenotypes

Erratum: DIRAS2 is Associated with Adult ADHD, Related Traits, and Co-Morbid Disorders

Increased locomotor activity via regulation of GABAergic signalling in foxp2 mutant zebrafish—implications for neurodevelopmental disorders

Identification of ADHD risk genes in extended pedigrees by combining linkage analysis and whole-exome sequencing

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