RagGTPases (Rags) play an essential role in the regulation of cell metabolism by controlling the activities of both mechanistic target of rapamycin complex 1 (mTORC1) and Transcription factor EB (TFEB). Here the authors review several diseases, termed ragopathies, that are associated with Rag dysfunction.
- Irene Sambri
- Marco Ferniani
- Andrea Ballabio
