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Karyopherins remodel the dynamic organization of the nuclear pore complex transport barrier

Kozai, Fernandez-Martinez et al. use high-speed atomic force microscopy to study the permeability barrier of yeast nuclear pore complexes. They show that karyopherins remodel a central plug that shapes barrier dynamics and disorder within the pore.

Toshiya Kozai
Javier Fernandez-Martinez
Roderick Y. H. Lim
ResearchOpen Access02 Dec 2025
Nature Cell Biology

Volume: 27, P: 2089-2101
Eye movements track prioritized auditory features in selective attention to natural speech

Anatomical overlap of respective brain regions suggests a joint network for attention and eye movements. Here, the authors show that gaze aligns with the acoustics of attended natural speech and differentiates between a target and a distractor in a cocktail party scenario.

Quirin Gehmacher
Juliane Schubert
Nathan Weisz
ResearchOpen Access01 May 2024
Nature Communications

Volume: 15, P: 1-15
Pupil-linked phasic arousal evoked by violation but not emergence of regularity within rapid sound sequences

The neurotransmitter Norepinephrine (NE) has been implicated in coding surprise during decision making. Here, the authors demonstrate that this extends to sensory processing: NE release is specific to unexpected events even on extremely rapid time scales and without explicit tracking of probability.

Sijia Zhao
Maria Chait
Hsin-I Liao
ResearchOpen Access06 Sept 2019
Nature Communications

Volume: 10, P: 1-16
Compounds that select against the tetracycline-resistance efflux pump

A high-throughput screen against the E. coli tetracycline-resistance efflux pump TetA identifies two ‘selection-inverting’ compounds that swap tetracycline resistance for resistance to another antibiotic, paving the way for two-phase antibiotic treatment protocols.

Laura K Stone
Michael Baym
Roy Kishony
Research19 Sept 2016
Nature Chemical Biology

Volume: 12, P: 902-904
Rapid Brain Responses to Familiar vs. Unfamiliar Music – an EEG and Pupillometry study

Robert Jagiello
Ulrich Pomper
Maria Chait
ResearchOpen Access30 Oct 2019
Scientific Reports

Volume: 9, P: 1-13
The impact of visual gaze direction on auditory object tracking

Ulrich Pomper
Maria Chait
ResearchOpen Access05 Jul 2017
Scientific Reports

Volume: 7, P: 1-16

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Karyopherins remodel the dynamic organization of the nuclear pore complex transport barrier

Eye movements track prioritized auditory features in selective attention to natural speech

Pupil-linked phasic arousal evoked by violation but not emergence of regularity within rapid sound sequences

Compounds that select against the tetracycline-resistance efflux pump

Rapid Brain Responses to Familiar vs. Unfamiliar Music – an EEG and Pupillometry study

The impact of visual gaze direction on auditory object tracking

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