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Showing 1–5 of 5 results
Advanced filters: Author: Maria Soledad Esposito Clear advanced filters

  • A combination of optogenetic, electrophysiological and neuroanatomical tracing methods defines midbrain periaqueductal grey circuits for specific defensive behaviours.

    • Philip Tovote
    • Maria Soledad Esposito
    • Andreas Lüthi
    Research
    Nature
    Volume: 534, P: 206-212

  • The authors use a combination of viral tracing and genetics to characterize the diversity of neurons projecting from mouse brainstem to motor neurons that control limb movements; in particular they discover that the medullary reticular formation ventral part (MdV) is functionally specialized for skilled forelimb motor control.

    • Maria Soledad Esposito
    • Paolo Capelli
    • Silvia Arber
    Research
    Nature
    Volume: 508, P: 351-356

  • Trans-neuronal transfer of pathogenic proteins has been demonstrated in multiple neurodegenerative diseases. Here the authors show in vitro and in a mouse model that mutant Huntingtin is also transferred from one neuron to another. This transfer requires exocytosis machinery and contributes to neurodegeneration.

    • Eline Pecho-Vrieseling
    • Claus Rieker
    • Francesco Paolo Di Giorgio
    Research
    Nature Neuroscience
    Volume: 17, P: 1064-1072

  • In the mouse caudal brainstem, functionally distinct neuronal subpopulations, which are distinguishable by neurotransmitter identity, connectivity and location, regulate locomotion parameters.

    • Paolo Capelli
    • Chiara Pivetta
    • Silvia Arber
    Research
    Nature
    Volume: 551, P: 373-377