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Showing 1–4 of 4 results

Advanced filters: Author: Maria V Abramova Clear advanced filters

Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

Genome-wide association analyses of 41,917 bipolar disorder cases and 371,549 controls of European ancestry provide new insights into the etiology of this disorder and identify novel therapeutic leads and potential opportunities for drug repurposing.

Niamh Mullins
Andreas J. Forstner
Ole A. Andreassen
Research17 May 2021
Nature Genetics

Volume: 53, P: 817-829
Genome-wide association study reveals two new risk loci for bipolar disorder

Bipolar disorder (BD) is a severe mood disorder, which has been shown to have a large genetic component. Here the authors identify two previously unreported BD risk loci and provide further insights into the biological mechanisms underlying BD development.

Thomas W. Mühleisen
Markus Leber
Sven Cichon
Research11 Mar 2014
Nature Communications

Volume: 5, P: 1-8
Downregulation of c-fos gene transcription in cells transformed by E1A and cHa-ras oncogenes: a role of sustained activation of MAP/ERK kinase cascade and of inactive chromatin structure at c-fos promoter

Alexander N Kukushkin
Maria V Abramova
Valery A Pospelov
Research11 Feb 2002
Oncogene

Volume: 21, P: 719-730
Genome-wide analysis implicates microRNAs and their target genes in the development of bipolar disorder

A J Forstner
A Hofmann
M M Nöthen
ResearchOpen Access10 Nov 2015
Translational Psychiatry

Volume: 5, P: e678