Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.
Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–1 of 1 results
Advanced filters: Author: Maria Wirzenius Clear advanced filters

  • The vascular endothelial growth factor (VEGF) receptor subtype VEGFR-3 is only expressed on lymphatic endothelium in adults. However, VEGFR-3 is upregulated in the vasculature of tumours by Notch signalling. VEGFR-3 inhibition interferes with tumour angiogenesis and tumour growth, in particular in combination with inhibitors of the VEGFR-2, suggesting that it represents a novel anti-angiogenic target for cancer therapy.

    • Tuomas Tammela
    • Georgia Zarkada
    • Kari Alitalo
    Research
    Nature
    Volume: 454, P: 656-660