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Advanced filters: Author: Marianne Flato Clear advanced filters

  • 2′-Deoxy-ADPR, formed from the combined action of NMNAT and CD38 in response to H2O2 signaling, activates TRPM2 ion channel currents more potently than the known agonist ADPR via a deceleration of channel inactivation and a higher average open probability.

    • Ralf Fliegert
    • Andreas Bauche
    • Andreas H Guse
    Research
    Nature Chemical Biology
    Volume: 13, P: 1036-1044