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DNH deoxyribonucleohelicates: self assembly of oligonucleosidic double-helical metal complexes

Ulrich Koert
Margaret M. Harding
Jean-Marie Lehn
Research26 Jul 1990
Nature

Volume: 346, P: 339-342
FGF acts as a co-transmitter through adenosine A_2A receptor to regulate synaptic plasticity

Adenosine receptor A_2AR is known to antagonize dopaminergic signaling in the striatum and its malfunctions have been implicated in various striatum-related diseases. Flajolet et al. show that A_2AR and fibroblast growth factor receptor interact to synergistically activate ERK1/2 pathway and that such interaction modulates the morphological changes of cultured neurons and synaptic plasticity of cortico-striatal synapses.

Marc Flajolet
Zhongfeng Wang
Paul Greengard
Research26 Oct 2008
Nature Neuroscience

Volume: 11, P: 1402-1409
Lysosomal positioning coordinates cellular nutrient responses

The subcellular position of lysosomes, whether adjacent to the plasma membrane or perinuclear, regulates mTOR signalling and autophagy in response to nutrient availablity. Lysosomal position is regulated by changes in intracellular pH.

Viktor I. Korolchuk
Shinji Saiki
David C. Rubinsztein
Research13 Mar 2011
Nature Cell Biology

Volume: 13, P: 453-460
Identification of Polo-like kinase 1 interaction inhibitors using a novel cell-based assay

Karine Normandin
Jean-François Lavallée
Vincent Archambault
ResearchOpen Access22 Nov 2016
Scientific Reports

Volume: 6, P: 1-20

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