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Showing 1–3 of 3 results
Advanced filters: Author: Marie-Eve Chagot Clear advanced filters

  • Choosing best chemical cross-linking (XL) reagents and conditions for studying protein-protein interactions in structural biology is laborious and lacks in accuracy. The authors develop here an accurate, fast, robust and quantiative denaturing mass photometry approach for screening of XL conditions.

    • Hugo Gizardin-Fredon
    • Paulo E. Santo
    • Sarah Cianférani
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-13

  • Biogenesis of small nucleolar RNAs ribonucleoproteins (snoRNPs) requires dedicated assembly machinery. Here, the authors show that a subset of snoRNP assembly factors interacts, genetically or directly, with factors modulating chromatin architecture, suggesting a link between ribosome formation and chromatin functions.

    • Benoît Bragantini
    • Christophe Charron
    • Bruno Charpentier
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-17

  • R2TP is an HSP90 co-chaperone composed of an RPAP3-PIH1D1 heterodimer, which binds two essential AAA+ ATPases RUVBL1/RUVBL2. Here authors use a structural approach to study RPAP3 and find an RPAP3-like protein (SPAG1) which also forms a co-chaperone complex with PIH1D2 and RUVBL1/2 enriched in testis.

    • Chloé Maurizy
    • Marc Quinternet
    • Edouard Bertrand
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-16