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Showing 1–7 of 7 results
Advanced filters: Author: Marieke Jepma Clear advanced filters

  • Jepma and colleagues provide evidence that prior beliefs about pain influence perceived intensity of pain, and the degree of learning about pain intensity. This finding helps to explain why beliefs are often resistant to updating with experience.

    • Marieke Jepma
    • Leonie Koban
    • Tor D. Wager
    Research
    Nature Human Behaviour
    Volume: 2, P: 838-855

  • Pain experience is highly individual, but its individual-specific brain features remain unclear. The authors identify brain regions with consistent versus variable representations of pain across a large sample of individuals.

    • Lada Kohoutová
    • Lauren Y. Atlas
    • Choong-Wan Woo
    Research
    Nature Neuroscience
    Volume: 25, P: 749-759

  • Our experience of pain can be affected by our expectations about how much pain we will feel. Here, the authors show that both social information-driven expectations, and those based on personal experience, are both able to modulate pain, but by different neural pathways.

    • Leonie Koban
    • Marieke Jepma
    • Tor D. Wager
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-13

  • Pain is affected by cerebral processes in addition to afferent nociceptive input. Here the authors develop an fMRI-based signature that predicts pain independent of the intensity of nociceptive signals and mediates the pain-modulating effects of several cognitive interventions.

    • Choong-Wan Woo
    • Liane Schmidt
    • Tor D. Wager
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-14

  • This study uses fMRI in humans to find that prediction errors about pain are encoded in the periaqueductal gray. Modeling inter-area connectivity suggests that the ventromedial prefrontal cortex and the putamen pass on a value-related signal to this midbrain structure, which then conveys predictor error signals to prefrontal regions that regulate behavior.

    • Mathieu Roy
    • Daphna Shohamy
    • Tor D Wager
    Research
    Nature Neuroscience
    Volume: 17, P: 1607-1612