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Showing 1–2 of 2 results
Advanced filters: Author: Maritza Puray-Chavez Clear advanced filters
  • Technical limitations in simultaneous microscopic visualization of HIV transcription from individual integration sites have curtailed progress in the field. Here the authors report a branched DNA in situ hybridization method for direct single-cell visualization of HIV DNA, RNA, and protein.

    • Maritza Puray-Chavez
    • Philip R. Tedbury
    • Stefan G. Sarafianos
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-11
  • Factors that determine the cellular tropism of SARS-CoV-2 beyond the host cell receptor, ACE2, are poorly defined. Here, the authors show that tonic activation of the cGAS-STING sensing pathway potently blocks SARS-CoV-2 replication in a subset of ACE2-expressing airway-derived cells.

    • Maritza Puray-Chavez
    • Jenna E. Eschbach
    • Sebla B. Kutluay
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-20