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Children born after assisted reproduction more commonly carry a mitochondrial genotype associating with low birthweight

Assisted reproduction increases low birthweight risk in children. This study finds a mitochondrial DNA genotype that is more common in ART children, associates to birthweight and that is linked to maternal ageing and to ovarian stimulation.

Joke Mertens
Florence Belva
Claudia Spits
ResearchOpen Access09 Feb 2024
Nature Communications

Volume: 15, P: 1-16
Gain of 1q confers an MDM4-driven growth advantage to undifferentiated and differentiating hESC while altering their differentiation capacity

Nuša Krivec
Edouard Couvreu de Deckersberg
Claudia Spits
ResearchOpen Access21 Nov 2024
Cell Death & Disease

Volume: 15, P: 1-14

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Children born after assisted reproduction more commonly carry a mitochondrial genotype associating with low birthweight

Gain of 1q confers an MDM4-driven growth advantage to undifferentiated and differentiating hESC while altering their differentiation capacity

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