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Showing 1–2 of 2 results
Advanced filters: Author: Marjolein Soethoudt Clear advanced filters

  • CB2 receptor agonists are developed as potential analgesics or immune-modulatory compounds. Here, the authors characterize the pharmacological properties of widely used CB2 receptor agonists and antagonists, recommending three that appear most suitable for in vitro and in vivostudies.

    • Marjolein Soethoudt
    • Uwe Grether
    • Mario van der Stelt
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-14

  • An inhibitor of NAPE-PLD involved in lipid biosynthesis lowers levels of the endocannabinoid anandamide and other N-acylethanolamines in cells and mouse brain and activates the hypothalamus–pituitary–adrenal axis and impaired fear extinction.

    • Elliot D. Mock
    • Mohammed Mustafa
    • Mario van der Stelt
    Research
    Nature Chemical Biology
    Volume: 16, P: 667-675