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Nature Chemical Biology (2)

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CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing’s sarcoma

The RNA endonuclease CPSF3 was identified as the cellular efficacy target of the small molecule JTE-607, revealing pre-mRNA processing as a vulnerability in cancers such as Ewing’s sarcoma that are characterized by aberrant transcription.

Nathan T. Ross
Felix Lohmann
Rohan E. J. Beckwith
Research09 Dec 2019
Nature Chemical Biology

Volume: 16, P: 50-59
Author Correction: CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing’s sarcoma

Nathan T. Ross
Felix Lohmann
Rohan E. J. Beckwith
Amendments and Corrections04 Mar 2020
Nature Chemical Biology

Volume: 16, P: 479

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CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing’s sarcoma

Author Correction: CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing’s sarcoma

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