Nature Search

Publisher Correction: Hazardous drinking and alcohol use disorders

James MacKillop
Roberta Agabio
Jürgen Rehm
Amendments and Corrections20 Sept 2024
Nature Reviews Disease Primers

Volume: 10, P: 1
Whole-genome sequencing of patients with rare diseases in a national health system

Whole-genome sequencing and phenotype data sharing are introduced in a national health system to streamline diagnosis and to discover coding and non-coding variants that cause rare diseases.

Ernest Turro
William J. Astle
Willem H. Ouwehand
Research24 Jun 2020
Nature

Volume: 583, P: 96-102
CXCR5 CAR-T cells simultaneously target B cell non-Hodgkin’s lymphoma and tumor-supportive follicular T helper cells

CAR-T cell therapy targeting CD19 is not as efficient to treat lymphoma with nodal dissemination as it is for B cell leukaemia. Here, the authors generate CAR-T cells against CXCR5 and show they inhibit tumour growth by depleting both B and follicular T helper cells in lymphoma models.

Mario Bunse
Janina Pfeilschifter
Uta E. Höpken
ResearchOpen Access11 Jan 2021
Nature Communications

Volume: 12, P: 1-19
Interplay of ferroptotic and apoptotic cell death and its modulation by BH3-mimetics

Yun Qiu
Juliana A. Hüther
Markus Rehm
ResearchOpen Access29 Apr 2025
Cell Death & Differentiation

P: 1-16
The apoptosome molecular timer synergises with XIAP to suppress apoptosis execution and contributes to prognosticating survival in colorectal cancer

Gavin Fullstone
Tabea L. Bauer
Markus Rehm
ResearchOpen Access27 Apr 2020
Cell Death & Differentiation

Volume: 27, P: 2828-2842
RALB GTPase: a critical regulator of DR5 expression and TRAIL sensitivity in KRAS mutant colorectal cancer

Hajrah Khawaja
Andrew Campbell
Sandra Van Schaeybroeck
ResearchOpen Access29 Oct 2020
Cell Death & Disease

Volume: 11, P: 1-18
Hazardous drinking and alcohol use disorders

Hazardous drinking and alcohol use disorder are associated with substantial harms to both the individual and others. This Primer discusses the epidemiology, mechanisms, diagnosis and management of these disorders, and also summarizes screening, prevention and the quality of life issues faced by individuals with these disorders.

James MacKillop
Roberta Agabio
Jürgen Rehm
Reviews22 Dec 2022
Nature Reviews Disease Primers

Volume: 8, P: 1-25
Simulating and predicting cellular and in vivo responses of colon cancer to combined treatment with chemotherapy and IAP antagonist Birinapant/TL32711

Nyree Crawford
Manuela Salvucci
Markus Rehm
Research02 Mar 2018
Cell Death & Differentiation

Volume: 25, P: 1952-1966
TAK1 suppresses RIPK1-dependent cell death and is associated with disease progression in melanoma

Biswajit Podder
Cristiano Guttà
Markus Rehm
Research08 Mar 2019
Cell Death & Differentiation

Volume: 26, P: 2520-2534
Bax retrotranslocation potentiates Bcl-x_L’s antiapoptotic activity and is essential for switch-like transitions between MOMP competency and resistance

Annika Hantusch
Kushal K. Das
Markus Rehm
ResearchOpen Access22 Mar 2018
Cell Death & Disease

Volume: 9, P: 1-13
Reconstructing temporal and spatial dynamics from single-cell pseudotime using prior knowledge of real scale cell densities

Karsten Kuritz
Daniela Stöhr
Frank Allgöwer
ResearchOpen Access27 Feb 2020
Scientific Reports

Volume: 10, P: 1-10
Phosphoprotein patterns predict trametinib responsiveness and optimal trametinib sensitisation strategies in melanoma

Jan Rožanc
Theodore Sakellaropoulos
Leonidas G. Alexopoulos
Research15 Oct 2018
Cell Death & Differentiation

Volume: 26, P: 1365-1378
ER stress-induced cell death proceeds independently of the TRAIL-R2 signaling axis in pancreatic β cells

Cathrin Hagenlocher
Robin Siebert
Markus Rehm
ResearchOpen Access24 Jan 2022
Cell Death Discovery

Volume: 8, P: 1-9
Proteasome inhibition triggers the formation of TRAIL receptor 2 platforms for caspase-8 activation that accumulate in the cytosol

Christian T. Hellwig
M. Eugenia Delgado
Markus Rehm
ResearchOpen Access05 Aug 2021
Cell Death & Differentiation

Volume: 29, P: 147-155
Marizomib sensitizes primary glioma cells to apoptosis induced by a latest-generation TRAIL receptor agonist

Chiara Boccellato
Emily Kolbe
Markus Rehm
ResearchOpen Access24 Jun 2021
Cell Death & Disease

Volume: 12, P: 1-11
Why Bax detection in >1400 publications might be flawed

Kristin Entrop
Senait Wieske
Markus Rehm
Comments & OpinionOpen Access05 Dec 2024
Cell Death & Disease

Volume: 15, P: 1-3
Low expression of pro-apoptotic proteins Bax, Bak and Smac indicates prolonged progression-free survival in chemotherapy-treated metastatic melanoma

Cristiano Guttà
Arman Rahman
Markus Rehm
ResearchOpen Access13 Feb 2020
Cell Death & Disease

Volume: 11, P: 1-12
Stress-induced TRAILR2 expression overcomes TRAIL resistance in cancer cell spheroids

Daniela Stöhr
Jens O. Schmid
Markus Rehm
ResearchOpen Access20 May 2020
Cell Death & Differentiation

Volume: 27, P: 3037-3052
Sensitization of glioblastoma cells to TRAIL-induced apoptosis by IAP- and Bcl-2 antagonism

Frank A. Lincoln
Dirke Imig
Markus Rehm
ResearchOpen Access01 Nov 2018
Cell Death & Disease

Volume: 9, P: 1-14
The FLAME-accelerated signalling tool (FaST) for facile parallelisation of flexible agent-based models of cell signalling

Gavin Fullstone
Cristiano Guttà
Markus Rehm
ResearchOpen Access20 Apr 2020
npj Systems Biology and Applications

Volume: 6, P: 1-10
Convergence of pathway analysis and pattern recognition predicts sensitization to latest generation TRAIL therapeutics by IAP antagonism

Vesna Vetma
Cristiano Guttà
Markus Rehm
ResearchOpen Access21 Feb 2020
Cell Death & Differentiation

Volume: 27, P: 2417-2432
Bcl-2-Ome – a database and interactive web service for dissecting the Bcl-2 interactome

Annika Hantusch
Thomas Brunner
Markus Rehm
CorrespondenceOpen Access11 Nov 2016
Cell Death & Differentiation

Volume: 24, P: 192
cFLIP downregulation is an early event required for endoplasmic reticulum stress-induced apoptosis in tumor cells

Rocío Mora-Molina
Daniela Stöhr
Abelardo López-Rivas
ResearchOpen Access03 Feb 2022
Cell Death & Disease

Volume: 13, P: 1-12
An atlas of inter- and intra-tumor heterogeneity of apoptosis competency in colorectal cancer tissue at single-cell resolution

Andreas Ulrich Lindner
Manuela Salvucci
Jochen H. M. Prehn
ResearchOpen Access09 Nov 2021
Cell Death & Differentiation

Volume: 29, P: 806-817
Transcriptional CDK inhibitors, CYC065 and THZ1 promote Bim-dependent apoptosis in primary and recurrent GBM through cell cycle arrest and Mcl-1 downregulation

Viktorija Juric
Lance Hudson
Brona M. Murphy
ResearchOpen Access03 Aug 2021
Cell Death & Disease

Volume: 12, P: 1-12
The BAX/BAK-like protein BOK is a prognostic marker in colorectal cancer

Steven Carberry
Beatrice D’Orsi
Jochen H. M. Prehn
ResearchOpen Access26 Jan 2018
Cell Death & Disease

Volume: 9, P: 1-10
Using plant physiological stable oxygen isotope models to counter food fraud

Florian Cueni
Daniel B. Nelson
Ansgar Kahmen
ResearchOpen Access27 Aug 2021
Scientific Reports

Volume: 11, P: 1-14
Response to “Addiction is a social disease: just as tenable as calling it a brain disease”

Markus Heilig
James MacKillop
Louk J. M. J. Vanderschuren
Correspondence09 Jun 2021
Neuropsychopharmacology

Volume: 46, P: 1713-1714
Addiction as a brain disease revised: why it still matters, and the need for consilience

Markus Heilig
James MacKillop
Louk J. M. J. Vanderschuren
ReviewsOpen Access22 Feb 2021
Neuropsychopharmacology

Volume: 46, P: 1715-1723
Apoptotic cell death in disease—Current understanding of the NCCD 2023

Ilio Vitale
Federico Pietrocola
Lorenzo Galluzzi
Reviews26 Apr 2023
Cell Death & Differentiation

Volume: 30, P: 1097-1154
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

Lorenzo Galluzzi
Ilio Vitale
Guido Kroemer
ReviewsOpen Access23 Jan 2018
Cell Death & Differentiation

Volume: 25, P: 486-541
Whither systems medicine?

Rolf Apweiler
Tim Beissbarth
Olaf Wolkenhauer
ReviewsOpen Access02 Mar 2018
Experimental & Molecular Medicine

Volume: 50, P: e453

Search

Publisher Correction: Hazardous drinking and alcohol use disorders

Whole-genome sequencing of patients with rare diseases in a national health system

CXCR5 CAR-T cells simultaneously target B cell non-Hodgkin’s lymphoma and tumor-supportive follicular T helper cells

Interplay of ferroptotic and apoptotic cell death and its modulation by BH3-mimetics

The apoptosome molecular timer synergises with XIAP to suppress apoptosis execution and contributes to prognosticating survival in colorectal cancer

RALB GTPase: a critical regulator of DR5 expression and TRAIL sensitivity in KRAS mutant colorectal cancer

Hazardous drinking and alcohol use disorders

Simulating and predicting cellular and in vivo responses of colon cancer to combined treatment with chemotherapy and IAP antagonist Birinapant/TL32711

TAK1 suppresses RIPK1-dependent cell death and is associated with disease progression in melanoma

Bax retrotranslocation potentiates Bcl-x_L’s antiapoptotic activity and is essential for switch-like transitions between MOMP competency and resistance

Reconstructing temporal and spatial dynamics from single-cell pseudotime using prior knowledge of real scale cell densities

Phosphoprotein patterns predict trametinib responsiveness and optimal trametinib sensitisation strategies in melanoma

ER stress-induced cell death proceeds independently of the TRAIL-R2 signaling axis in pancreatic β cells

Proteasome inhibition triggers the formation of TRAIL receptor 2 platforms for caspase-8 activation that accumulate in the cytosol

Marizomib sensitizes primary glioma cells to apoptosis induced by a latest-generation TRAIL receptor agonist

Why Bax detection in >1400 publications might be flawed

Low expression of pro-apoptotic proteins Bax, Bak and Smac indicates prolonged progression-free survival in chemotherapy-treated metastatic melanoma

Stress-induced TRAILR2 expression overcomes TRAIL resistance in cancer cell spheroids

Sensitization of glioblastoma cells to TRAIL-induced apoptosis by IAP- and Bcl-2 antagonism

The FLAME-accelerated signalling tool (FaST) for facile parallelisation of flexible agent-based models of cell signalling

Convergence of pathway analysis and pattern recognition predicts sensitization to latest generation TRAIL therapeutics by IAP antagonism

Bcl-2-Ome – a database and interactive web service for dissecting the Bcl-2 interactome

cFLIP downregulation is an early event required for endoplasmic reticulum stress-induced apoptosis in tumor cells

An atlas of inter- and intra-tumor heterogeneity of apoptosis competency in colorectal cancer tissue at single-cell resolution

Transcriptional CDK inhibitors, CYC065 and THZ1 promote Bim-dependent apoptosis in primary and recurrent GBM through cell cycle arrest and Mcl-1 downregulation

The BAX/BAK-like protein BOK is a prognostic marker in colorectal cancer

Using plant physiological stable oxygen isotope models to counter food fraud

Response to “Addiction is a social disease: just as tenable as calling it a brain disease”

Addiction as a brain disease revised: why it still matters, and the need for consilience

Apoptotic cell death in disease—Current understanding of the NCCD 2023

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

Whither systems medicine?

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