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Advanced filters: Author: Markus Winterberg Clear advanced filters

A high-sensitivity HPLC assay for measuring intracellular Na⁺ and K⁺ and its application to Plasmodium falciparum infected erythrocytes

Markus Winterberg
Kiaran Kirk
ResearchOpen Access07 Jul 2016
Scientific Reports

Volume: 6, P: 1-6
A lactate and formate transporter in the intraerythrocytic malaria parasite, Plasmodium falciparum

Malaria parasites generate metabolic energy through anaerobic glycolysis, yielding lactate that is then secreted out of the parasite cell by an unknown transporter. Here, Marchetti et al. identify and characterize a transporter that may be carrying out such a function in Plasmodium.

Rosa V. Marchetti
Adele M. Lehane
Kiaran Kirk
Research31 Mar 2015
Nature Communications

Volume: 6, P: 1-7
Chemical and genetic validation of thiamine utilization as an antimalarial drug target

The malaria parasite Plasmodium falciparum utilizes thiamine for the production of essential enzymatic cofactors. Chan et al. show that inhibition of thiamine utilization with oxythiamine inhibits proliferation of P. falciparumand reduces parasite growth in a mouse model of malaria infection.

Xie Wah Audrey Chan
Carsten Wrenger
Kevin J. Saliba
ResearchOpen Access27 Jun 2013
Nature Communications

Volume: 4, P: 1-11
Amino acid derangements in adults with severe falciparum malaria

Stije J. Leopold
Siribha Apinan
Arjen M. Dondorp
ResearchOpen Access29 Apr 2019
Scientific Reports

Volume: 9, P: 1-9

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