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Showing 1–2 of 2 results
Advanced filters: Author: Marlies E. Oomen Clear advanced filters
  • It remains impossible using conventional Hi-C to differentiate interactions between and along sister chromatids. SisterC relies on selective destruction of nascent DNA and in combination with Hi-C offers a means to study intra- and inter-sister interactions independently.

    • Marlies E. Oomen
    • Adam K. Hedger
    • Job Dekker
    Research
    Nature Methods
    Volume: 17, P: 1002-1009
  • This analysis systematically evaluates cross-linking chemistry and chromatin fragmentation strategies commonly used in 3C assays and introduces an improved Hi-C protocol for detecting loops and compartments.

    • Betul Akgol Oksuz
    • Liyan Yang
    • Job Dekker
    ResearchOpen Access
    Nature Methods
    Volume: 18, P: 1046-1055