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Showing 1–3 of 3 results
Advanced filters: Author: Marta Grzelak Clear advanced filters
  • There is a need to understand how mammary epithelial cells respond to changes at various developmental stages. Here, the authors use single-cell RNA sequencing of mammary epithelial cells at different adult developmental stages, identifying different cell types and charting their developmental trajectory.

    • Karsten Bach
    • Sara Pensa
    • Walid T. Khaled
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-11
  • This Review discusses advances in RNA-sequencing technologies and methods over the past decade and outlines adaptations that are enabling a fuller understanding of RNA biology, from when and where an RNA is expressed to the structures it adopts.

    • Rory Stark
    • Marta Grzelak
    • James Hadfield
    Reviews
    Nature Reviews Genetics
    Volume: 20, P: 631-656
  • Anna Biernacka, Yingjie Zhu et al. present i-BLESS, a universal method for detecting genome-wide DNA double strand breaks, optimized here for yeast. By immobilizing cells on agarose beads, the authors are able to achieve efficient diffusion of reagents and labeling of double strand breaks, including ultra-rare breaks such as those at G-quadruplexes.

    • Anna Biernacka
    • Yingjie Zhu
    • Krzysztof Ginalski
    ResearchOpen Access
    Communications Biology
    Volume: 1, P: 1-9