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Showing 1–3 of 3 results
Advanced filters: Author: Marta Ukleja Clear advanced filters

  • CCR4-NOT is a protein complex involved in a variety of important genetic processes. Here, the authors report the mid-resolution structure of this complex, and model the positions and contacts between the subunits, providing structural support for the previously reported functions of the complex.

    • Marta Ukleja
    • Jorge Cuellar
    • Jose M. Valpuesta
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-11

  • The function of many bacterial processes depends on the formation of functional membrane microdomains (FMMs), which resemble the lipid rafts of eukaryotic cells. Here, Ukleja et al. show that FMMs mediate ATP-independent stabilization of unfolded proteins, which is essential for bacterial viability under cellular stress and during infection.

    • Marta Ukleja
    • Lara Kricks
    • Daniel Lopez
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-21

  • Cryo-electron microscopy structures of a 2.8 megadalton bacterial type IV secretion system encoded by the plasmid R388 and comprising 92 polypeptides provide insights into the stepwise mechanism of pilus assembly.

    • Kévin Macé
    • Abhinav K. Vadakkepat
    • Gabriel Waksman
    ResearchOpen Access
    Nature
    Volume: 607, P: 191-196