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Showing 1–4 of 4 results

Advanced filters: Author: Martin A. Cheever Clear advanced filters

Immune cell topography predicts response to PD-1 blockade in cutaneous T cell lymphoma

PD-1 blockade is effective for only a subset of patients with cutaneous T cell lymphomas. Here, the authors report a spatial biomarker that uses immune and cancer cell topography to predict response to PD-1 blockade in this disease.

Darci Phillips
Magdalena Matusiak
Garry P. Nolan
ResearchOpen Access18 Nov 2021
Nature Communications

Volume: 12, P: 1-18
Flt3 ligand augments immune responses to anti-DEC-205-NY-ESO-1 vaccine through expansion of dendritic cell subsets

Bhardwaj et al. report that adding Flt3 ligand to the treatment strategy effectively increased DC populations and increased T-cell responses in a randomized phase II trial of a DC-targeted vaccine for the melanoma antigen NY-ESO-1.

Nina Bhardwaj
Philip A. Friedlander
Steven P. Fling
Research16 Nov 2020
Nature Cancer

Volume: 1, P: 1204-1217
Characterization of KLK4 expression and detection of KLK4-specific antibody in prostate cancer patient sera

Craig H Day
Gary R Fanger
Yoshihiro Watanabe
Research09 Oct 2002
Oncogene

Volume: 21, P: 7114-7120
Post-translational modifications of the Fragile X Mental Retardation Protein in neuronal function and dysfunction

Marta Prieto
Alessandra Folci
Stéphane Martin
Reviews10 Dec 2019
Molecular Psychiatry

Volume: 25, P: 1688-1703