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Author Correction: Enhanced nucleotide chemistry and toehold nanotechnology reveals lncRNA spreading on chromatin

Martin Machyna
Lea Kiefer
Matthew D. Simon
Amendments and Corrections18 Mar 2020
Nature Structural & Molecular Biology

Volume: 27, P: 400
The coilin N-terminus mediates multivalent interactions between coilin and Nopp140 to form and maintain Cajal bodies

Cajal bodies are membraneless organelles scaffolded by coilin protein. Here, coilin–coilin and coilin–Nopp140 interaction sites are identified and perturbed, revealing coilin’s capacity to form long fibrils and be remodeled into spherical structures.

Edward Courchaine
Sara Gelles-Watnick
Karla M. Neugebauer
ResearchOpen Access12 Oct 2022
Nature Communications

Volume: 13, P: 1-13
Acetyl-methyllysine marks chromatin at active transcription start sites

Cellular lysine residues can be both methylated and acetylated on the same sidechain to form N^ε-acetyl-N^ε-methyllysine (Kacme), which is found on histone H4 across a range of species and across mammalian tissues and is associated with active chromatin.

William J. Lu-Culligan
Leah J. Connor
Matthew D. Simon
Research20 Sept 2023
Nature

Volume: 622, P: 173-179
Structural basis for dimethylarginine recognition by the Tudor domains of human SMN and SPF30 proteins

Dimethylated arginine (DMA) marks are recognized by Tudor domain–containing proteins and play a role in the assembly of ribonucleoprotein complexes. Structural analysis of prototypic Tudor domains from SMN and SPF30 in complex with DMA reveals the recognition mode of DMA, enabling the design of an optimized binding pocket.

Konstantinos Tripsianes
Tobias Madl
Michael Sattler
Research20 Nov 2011
Nature Structural & Molecular Biology

Volume: 18, P: 1414-1420
Enhanced nucleotide chemistry and toehold nanotechnology reveals lncRNA spreading on chromatin

thCHART, a hybridization capture approach using biotinylated LNA-oligonucleotides with toehold architecture, improves the specificity of RNA enrichment and enables detection of the chromosomal spreading pattern of Drosophila roX2 lncRNA under different cellular conditions.

Martin Machyna
Lea Kiefer
Matthew D. Simon
Research10 Mar 2020
Nature Structural & Molecular Biology

Volume: 27, P: 297-304

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Author Correction: Enhanced nucleotide chemistry and toehold nanotechnology reveals lncRNA spreading on chromatin

The coilin N-terminus mediates multivalent interactions between coilin and Nopp140 to form and maintain Cajal bodies

Acetyl-methyllysine marks chromatin at active transcription start sites

Structural basis for dimethylarginine recognition by the Tudor domains of human SMN and SPF30 proteins

Enhanced nucleotide chemistry and toehold nanotechnology reveals lncRNA spreading on chromatin

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