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Showing 451–500 of 704 results

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Publisher Correction: Whole-genome sequencing of a sporadic primary immunodeficiency cohort

James E. D. Thaventhiran
Hana Lango Allen
Kenneth G. C. Smith
Amendments and Corrections17 Jul 2020
Nature

Volume: 584, P: E2
The Alien Flora of Australia (AFA), a unified Australian national dataset on plant invasion

I. Martín-Forés
G. R. Guerin
B. Sparrow
ResearchOpen Access27 Nov 2023
Scientific Data

Volume: 10, P: 1-9
Stickler syndrome – lessons from a national cohort

M. P. Snead
A. J. Richards
A. V. Poulson
ResearchOpen Access05 Oct 2021
Eye

Volume: 36, P: 1966-1972
Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases

Mendelian randomization (MR) and colocalization analyses are used to estimate causal effects of 1,002 plasma proteins on 225 phenotypes. Evidence from drug developmental programs shows that target-indication pairs with MR and colocalization support were more likely to be approved, highlighting the value of this approach for prioritizing therapeutic targets.

Jie Zheng
Valeriia Haberland
Tom R. Gaunt
Research07 Sept 2020
Nature Genetics

Volume: 52, P: 1122-1131
Toward a Neuro-Cognitive Animal Model of the Cognitive Symptoms of Schizophrenia: Disruption of Cortical Cholinergic Neurotransmission Following Repeated Amphetamine Exposure in Attentional Task-Performing, but Not Non-Performing, Rats

Rouba Kozak
Vicente Martinez
Martin Sarter
Research14 Feb 2007
Neuropsychopharmacology

Volume: 32, P: 2074-2086
Author Correction: The evolution of lung cancer and impact of subclonal selection in TRACERx

Alexander M. Frankell
Michelle Dietzen
Charles Swanton
Amendments and CorrectionsOpen Access04 Jul 2024
Nature

Volume: 631, P: E15
Clinical and virologic characteristics of the first 12 patients with coronavirus disease 2019 (COVID-19) in the United States

Detailed clinical and virologic characteristics of the first 12 individuals with COVID-19 in the United States from the US Centers for Disease Control and Prevention.

Stephanie A. Kujawski
Karen K. Wong
Jing Zhang
Research23 Apr 2020
Nature Medicine

Volume: 26, P: 861-868
Publisher Correction: Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer

Kroopa Joshi
Marc Robert de Massy
Benny Chain
Amendments and Corrections03 Jun 2020
Nature Medicine

Volume: 26, P: 1148
A population-scale temporal case–control evaluation of COVID-19 disease phenotype and related outcome rates in patients with cancer in England (UKCCP)

Thomas Starkey
Maria C. Ionescu
Lennard Y. W. Lee
ResearchOpen Access25 Jul 2023
Scientific Reports

Volume: 13, P: 1-8
Publisher Correction: Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse

Francesca Chemi
Dominic G. Rothwell
Jason Lester
Amendments and Corrections03 Jun 2020
Nature Medicine

Volume: 26, P: 1147
The role of recessive inheritance in early-onset epileptic encephalopathies: a combined whole-exome sequencing and copy number study

Sorina M. Papuc
Lucia Abela
Anita Rauch
ResearchOpen Access14 Dec 2018
European Journal of Human Genetics

Volume: 27, P: 408-421
Large scale automated phylogenomic analysis of bacterial isolates and the Evergreen Online platform

Szarvas et al. present a phylogenomic pipeline ‘PAPABAC’ paired with a web platform ‘Evergreen Online’ that performs daily clustering of publicly released pathogen genomes and acts as a genomic surveillance system for a targeted set of pathogen species. The method is accurate at grouping outbreak strains together and discriminating them from non-outbreak strains.

Judit Szarvas
Johanne Ahrenfeldt
Ole Lund
ResearchOpen Access20 Mar 2020
Communications Biology

Volume: 3, P: 1-10
Author Correction: Large-scale targeted sequencing identifies risk genes for neurodevelopmental disorders

Tianyun Wang
Kendra Hoekzema
Evan E. Eichler
Amendments and CorrectionsOpen Access21 Oct 2020
Nature Communications

Volume: 11, P: 1
CrispRVariants charts the mutation spectrum of genome engineering experiments

Helen Lindsay
Alexa Burger
Mark D Robinson
Correspondence12 Jul 2016
Nature Biotechnology

Volume: 34, P: 701-702
Bridging The Age Gap: observational cohort study of effects of chemotherapy and trastuzumab on recurrence, survival and quality of life in older women with early breast cancer

Alistair Ring
Nicolò Matteo Luca Battisti
Matt Winter
ResearchOpen Access10 May 2021
British Journal of Cancer

Volume: 125, P: 209-219
Anomalously high geothermal flux near the South Pole

T. A. Jordan
C. Martin
M. Siegert
ResearchOpen Access14 Nov 2018
Scientific Reports

Volume: 8, P: 1-8
Detection of the Moderately Beneficial Cognitive Effects of Low-Dose Treatment with Haloperidol or Clozapine in an Animal Model of the Attentional Impairments of Schizophrenia

Vicente Martinez
Martin Sarter
Research19 Dec 2007
Neuropsychopharmacology

Volume: 33, P: 2635-2647
A clonal expression biomarker associates with lung cancer mortality

TRACERx Lung: Intratumoral transcriptional heterogeneity, which often hinders the development of clinically useful RNA-expression-biased biomarkers for cancer, can now be overcome with an approach for the identification of clonal expression biomarkers.

Dhruva Biswas
Nicolai J. Birkbak
Angeles Montero
Research07 Oct 2019
Nature Medicine

Volume: 25, P: 1540-1548
Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse

Pulmonary venous tumor cells disseminating before tumor resection are heterogeneous, predict relapse and seed future metastasis of lung cancer

Francesca Chemi
Dominic G. Rothwell
Jason Lester
Research07 Oct 2019
Nature Medicine

Volume: 25, P: 1534-1539
Fibroblast Growth Factor 2 Activation of Stromal Cell Vascular Endothelial Growth Factor Expression and Angiogenesis

Kevin P Claffey
Kristin Abrams
Martin Keough
Research01 Jan 2001
Laboratory Investigation

Volume: 81, P: 61-75
Tracking excited-state charge and spin dynamics in iron coordination complexes

Femtosecond resolution X-ray fluorescence spectroscopy is shown to track the charge and spin dynamics triggered when an iron coordination complex is excited by light, and establishes the critical role of intermediate spin states in the de-excitation process.

Wenkai Zhang
Roberto Alonso-Mori
Kelly J. Gaffney
Research07 May 2014
Nature

Volume: 509, P: 345-348
Mutations causing medullary cystic kidney disease type 1 lie in a large VNTR in MUC1 missed by massively parallel sequencing

Anthony Bleyer, Eric Lander, Mark Daly and colleagues show that frameshift mutations in a large VNTR of MUC1 cause medullary cystic kidney disease type 1. Their discovery sheds light on the biology of this disease and highlights challenges in using massively parallel sequencing technologies to characterize certain types of sequence variants.

Andrew Kirby
Andreas Gnirke
Mark J Daly
Research10 Feb 2013
Nature Genetics

Volume: 45, P: 299-303
A gravitational wave observatory operating beyond the quantum shot-noise limit

‘Squeezed light’ enables quantum noise in one aspect of light to be reduced by increasing the noise, or more accurately the quantum uncertainty, of a complementary aspect. This has now been used to push the detectors at the heart of the GEO600 gravitational wave observatory to unprecedented levels of sensitivity.

J. Abadie
B. P. Abbott
J. Zweizig
Research11 Sept 2011
Nature Physics

Volume: 7, P: 962-965
An upper limit on the stochastic gravitational-wave background of cosmological origin

A stochastic background of gravitational waves is expected to arise from a superposition of a large number of unresolved gravitational-wave sources and should carry unique signatures from the earliest epochs of the Universe. Limits on the amplitude of the stochastic gravitational-wave background are now reported using the data from a two-year science run of the Laser Interferometer Gravitational-wave Observatory. These limits rule out certain models of early Universe evolution.

B. P. Abbott
R. Abbott
J. Zweizig
Research20 Aug 2009
Nature

Volume: 460, P: 990-994
Genome-wide association analyses identify new susceptibility loci for oral cavity and pharyngeal cancer

Paul Brennan and colleagues perform genome-wide association analysis for oral cavity and pharyngeal cancer in trans-ancestry populations. They find seven new loci across different cancer subtypes, including a protective association in the HLA region that has a stronger effect in patients with human papillomavirus–positive cancers.

Corina Lesseur
Brenda Diergaarde
Paul Brennan
Research17 Oct 2016
Nature Genetics

Volume: 48, P: 1544-1550
Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals

A large-scale GWAS provides insight on diabetes-dependent genetic effects on the glomerular filtration rate, a common metric to monitor kidney health in disease.

Thomas W. Winkler
Humaira Rasheed
Iris M. Heid
ResearchOpen Access13 Jun 2022
Communications Biology

Volume: 5, P: 1-20
A systematic approach to the modelling and comparison of the geometries of spherical electrodes in inertial electrostatic confinement fusion devices

Jan-Philipp Wulfkühler
Hai-Dang Nguyen
Martin Tajmar
ResearchOpen Access27 Jan 2024
Scientific Reports

Volume: 14, P: 1-23
Author Correction: Genomic analysis of sewage from 101 countries reveals global landscape of antimicrobial resistance

Patrick Munk
Christian Brinch
Frank M. Aarestrup
Amendments and CorrectionsOpen Access12 Jan 2023
Nature Communications

Volume: 14, P: 1
A comparative genomics multitool for scientific discovery and conservation

A whole-genome alignment of 240 phylogenetically diverse species of eutherian mammal—including 131 previously uncharacterized species—from the Zoonomia Project provides data that support biological discovery, medical research and conservation.

Diane P. Genereux
Aitor Serres
Elinor K. Karlsson
ResearchOpen Access11 Nov 2020
Nature

Volume: 587, P: 240-245
Solving patients with rare diseases through programmatic reanalysis of genome-phenome data

Leslie Matalonga
Carles Hernández-Ferrer
Andreas Rump
ResearchOpen Access01 Jun 2021
European Journal of Human Genetics

Volume: 29, P: 1337-1347
YAP is essential for tissue tension to ensure vertebrate 3D body shape

D’Arcy Thompson predicted a century ago that animal body shape is conditioned by gravity, but there has been no animal model to study how cellular forces are coordinated to generate body shapes that withstand gravity; the hirame medaka fish mutant, with pronounced body flattening, reveals how the hirame/YAP gene controls gravity-resisting cellular forces to produce complex 3D organs and body shapes.

Sean Porazinski
Huijia Wang
Makoto Furutani-Seiki
Research16 Mar 2015
Nature

Volume: 521, P: 217-221
Disruption prediction with artificial intelligence techniques in tokamak plasmas

Tokamak plasmas are prone to sudden collapses that terminate the nuclear fusion reactions. This perspective discusses the prediction of these so-called disruptions with artificial intelligence techniques.

J. Vega
A. Murari
I. Zychor
Reviews06 Jun 2022
Nature Physics

Volume: 18, P: 741-750
Exposure to airborne bacteria depends upon vertical stratification and vegetation complexity

Jake M. Robinson
Christian Cando-Dumancela
Martin F. Breed
ResearchOpen Access04 May 2021
Scientific Reports

Volume: 11, P: 1-16
Author Correction: A detailed map of Higgs boson interactions by the ATLAS experiment ten years after the discovery

G. Aad
B. Abbott
L. Zwalinski
Amendments and CorrectionsOpen Access18 Oct 2023
Nature

Volume: 623, P: E5
Tetracycline use and risk of incident skin cancer: a prospective study

Wen-Qing Li
Aaron M Drucker
Abrar A Qureshi
ResearchOpen Access26 Oct 2017
British Journal of Cancer

Volume: 118, P: 294-298
Inactivation of Adenosine A_2A Receptors Selectively Attenuates Amphetamine-Induced Behavioral Sensitization

Jiang-Fan Chen
Rosario Moratalla
Michael A Schwarzschild
Research10 Jan 2003
Neuropsychopharmacology

Volume: 28, P: 1086-1095
Gene and pathway level analyses of germline DNA-repair gene variants and prostate cancer susceptibility using the iCOGS-genotyping array

Edward J Saunders
Tokhir Dadaev
Zsofia Kote-Jarai
ResearchOpen Access10 Mar 2016
British Journal of Cancer

Volume: 114, P: 945-952
Publisher Correction: A clonal expression biomarker associates with lung cancer mortality

Dhruva Biswas
Nicolai J. Birkbak
Angeles Montero
Amendments and Corrections03 Jun 2020
Nature Medicine

Volume: 26, P: 1148
Functional soft materials from metallopolymers and metallosupramolecular polymers

The presence of metal centres in synthetic polymers can impart interesting functionality on the resultant material. This Review Article focuses on the use of metal-containing polymers in a diverse range of applications, for example, in emissive and optical materials, in nanomaterials, as sensors, stimuli-responsive gels, catalysts and artifical metalloenzymes.

George R. Whittell
Martin D. Hager
Ian Manners
Reviews21 Feb 2011
Nature Materials

Volume: 10, P: 176-188
Bispecific repurposed medicines targeting the viral and immunological arms of COVID-19

Martin A. Redhead
C. David Owen
Martin A. Walsh
ResearchOpen Access24 Jun 2021
Scientific Reports

Volume: 11, P: 1-14
Atomic model for the membrane-embedded V_O motor of a eukaryotic V-ATPase

The structure of the V_O subcomplex of yeast V-ATPase, solved by electron cryomicroscopy, reveals a new subunit and suggests a mechanism for the translocation of protons across membranes.

Mohammad T. Mazhab-Jafari
Alexis Rohou
John L. Rubinstein
Research24 Oct 2016
Nature

Volume: 539, P: 118-122
The Effects of Acute and Chronic Haloperidol Treatment on Dopamine Release Mediated by the Medial Forebrain Bundle in the Striatum and Nucleus Accumbens

Michael F Egan
Stanislaw J Chrapusta
Richard Jed Wyatt
Research01 Mar 1996
Neuropsychopharmacology

Volume: 14, P: 211-223
Amphetamine Primes Motivation to Gamble and Gambling-Related Semantic Networks in Problem Gamblers

Martin Zack
Constantine X Poulos
Research22 Oct 2003
Neuropsychopharmacology

Volume: 29, P: 195-207
Geospatial immune variability illuminates differential evolution of lung adenocarcinoma

Multiregion spatial histology, exome and transcriptome data from patients with non-small cell lung cancer suggest that cancer subclones from immune cold regions diversify later than subclones from immune hot regions

Khalid AbdulJabbar
Shan E. Ahmed Raza
Yinyin Yuan
Research27 May 2020
Nature Medicine

Volume: 26, P: 1054-1062
Lack of detectable neoantigen depletion signals in the untreated cancer genome

Pan-cancer genomic analyses based on HLA affinity predictions show that apparent neoantigen depletion signals in untreated tumors become negligible after correction for trinucleotide-based mutational signatures.

Jimmy Van den Eynden
Alejandro Jiménez-Sánchez
Erik Larsson
Research25 Nov 2019
Nature Genetics

Volume: 51, P: 1741-1748
Research priorities for COVID-19 sensor technology

Allison Tong
Tania C. Sorrell
Hans Zoellner
Correspondence18 Jan 2021
Nature Biotechnology

Volume: 39, P: 144-147
Genetically edited human placental organoids cast new light on the role of ACE2

Anya L. Arthurs
Bianca Dietrich
Claire T. Roberts
ResearchOpen Access07 Feb 2025
Cell Death & Disease

Volume: 16, P: 1-12
Isovists compactness and stairs as predictors of evacuation route choice

Dajana Snopková
Laure De Cock
Petr Kubíček
ResearchOpen Access20 Feb 2023
Scientific Reports

Volume: 13, P: 1-15
Using X-ray velocimetry to measure lung function and assess the efficacy of a pseudomonas aeruginosa bacteriophage therapy for cystic fibrosis

Stephanie A. Harker
Melissa Preissner
Kaye S. Morgan
ResearchOpen Access29 Nov 2024
Scientific Reports

Volume: 14, P: 1-14
Mutations in DCC cause isolated agenesis of the corpus callosum with incomplete penetrance

Linda Richards, Paul Lockhart, Christel Depienne and colleagues identify heterozygous DCC mutations in four families and five sporadic individuals with agenesis of the corpus callosum (ACC). They report that DCC mutations result in variable dominant phenotypes with incomplete penetrance, including mirror movements and ACC associated with a favorable developmental prognosis.

Ashley P L Marsh
Delphine Heron
Christel Depienne
Research27 Feb 2017
Nature Genetics

Volume: 49, P: 511-514

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