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Showing 1–7 of 7 results
Advanced filters: Author: Marylene Leboeuf Clear advanced filters

  • Polyphenols have partial antidepressant effect without known mechanism. Here, the authors identify two phytochemicals from bioactive dietary polyphenols, show their antidepressant effect in a rodent model of depression, and that this effect is mediated by epigenetic and anti-inflammatory mechanisms.

    • Jun Wang
    • Georgia E. Hodes
    • Giulio M. Pasinetti
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-14

  • Chow et al. report a crucial role for macrophages in erythroblast development in mice. Under conditions that induce new red blood cell formation, macrophage depletion impaired red blood cell recovery. Conversely, macrophage depletion normalized red blood cell counts in a mouse model of polycythemia vera, pointing to a potential new therapeutic strategy for this disease. Findings similar to these are reported in an accompanying paper by Ramos et al.

    • Andrew Chow
    • Matthew Huggins
    • Paul S Frenette
    Research
    Nature Medicine
    Volume: 19, P: 429-436

  • The transcriptional regulation of commitment to the dendritic cell (DC) lineage and functional specialization of DCs in vivo is poorly understood. In this Resource, Merad and colleagues identify the lineage relationships among various tissue DC subsets.

    • Jennifer C Miller
    • Brian D Brown
    • Christophe Benoist
    Research
    Nature Immunology
    Volume: 13, P: 888-899

  • Nature Immunology’s 20th anniversary is a good opportunity to reminisce about the ImmGen collective endeavor — its goals, successes and horror stories — and the group’s exploration of various modes of scientific publishing.

    • Stephanie Vargas Aguilar
    • Oscar Aguilar
    • Caroline Ziemkiewicz
    Comments & Opinion
    Nature Immunology
    Volume: 21, P: 700-703