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Showing 1–3 of 3 results
Advanced filters: Author: Masaaki Sokabe Clear advanced filters

  • The authors report the structure of a human 48S translation initiation complex, finding a second molecule of eIF4A at the mRNA entry site, apart from the one present within the cap-binding complex eIF4F. This second entry-site eIF4A may be responsible for unwinding mRNA secondary structure.

    • Jailson Brito Querido
    • Masaaki Sokabe
    • V. Ramakrishnan
    ResearchOpen Access
    Nature Structural & Molecular Biology
    Volume: 31, P: 455-464

  • Single-molecule spectroscopy and structural studies were used to examine the dynamics of association of eIF1A and eIF5B with the human translation initiation complex and their role in presenting tRNA to the complex to initiate translation.

    • Christopher P. Lapointe
    • Rosslyn Grosely
    • Joseph D. Puglisi
    Research
    Nature
    Volume: 607, P: 185-190