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Showing 1–1 of 1 results
Advanced filters: Author: Masai Rains Clear advanced filters
  • Coactivator-associated arginine methyltransferase 1 (CARM1) is an important target in hematologic malignancies. In this work, the authors show that the hyperactivation of Janus kinase 2 (JAK2) by the V617F mutation phosphorylates CARM1 which regulates its methyltransferase activity and alters its target specificity.

    • Hidehiro Itonaga
    • Adnan K. Mookhtiar
    • Stephen D. Nimer
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-19