In higher eukaryotes, during mitosis the nuclear transport system Ran organises spindle formation, but in yeast, such targets for Ran had not yet been identified. Here Sato and Toda show that in fission yeast, the microtubule-associated protein Alp7/TACC is a critical target for Ran and contributes to spindle formation.
- Masamitsu Sato
- Takashi Toda