Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–7 of 7 results
Advanced filters: Author: Massimo Mangiola Clear advanced filters

  • Together with a companion paper, molecular details of immune responses in a pig-to-human xenotransplantation are identified through dense longitudinal multi-omics profiling of the xenograft and the host recipient, across the 61-day procedure.

    • Eloi Schmauch
    • Brian D. Piening
    • Brendan J. Keating
    Research
    Nature
    Volume: 650, P: 205-217

  • Xenotransplantation of a genetically edited pig kidney with a thymic autograft into a brain-dead human for 61 days with immunosuppression resulted in stable kidney function without proteinuria, and xenograft rejection was treated and reversed by the end of the study.

    • Robert A. Montgomery
    • Jeffrey M. Stern
    • Megan Sykes
    Research
    Nature
    Volume: 650, P: 218-229

  • Kidney transplants are at risk of graft failure due to immune system rejection. Here, the authors assess a broad range of clinical and immunological baseline variables in a large, unselected kidney transplant cohort, providing further insights into factors associated with antibody-mediated rejection

    • Zeynep Demir
    • Marc Raynaud
    • Alexandre Loupy
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-11

  • In a short-term study in which hearts from gene-edited pigs were transplanted into two recently deceased human recipients, the hearts were able to function for the duration of the study without signs of rejection and without evidence of pig virus transmission, encouraging further clinical study of cardiac xenotransplantation.

    • Nader Moazami
    • Jeffrey M. Stern
    • Robert A. Montgomery
    Research
    Nature Medicine
    Volume: 29, P: 1989-1997

  • Multi-omics profiling of the blood and heart of two human decedents receiving pig heart xenografts, including single-cell studies, reveals early immune responses and perioperative cardiac xenograft dysfunction in one of the two decedents, which may be due to mismatched heart size and/or insufficient immunosuppression.

    • Eloi Schmauch
    • Brian Piening
    • Brendan J. Keating
    Research
    Nature Medicine
    Volume: 30, P: 1448-1460

  • Heart transplantation for patients with advanced heart failure is limited by a shortage of donor organs. In this Review, Jou and colleagues explore the options to increase the supply of donor hearts, including transplantation from donors with HCV, HIV or SARS-CoV-2 infection, national opt-out organ donation policies, donation after circulatory death, and xenotransplantation.

    • Stephanie Jou
    • Sean R. Mendez
    • Claudia Gidea
    Reviews
    Nature Reviews Cardiology
    Volume: 21, P: 25-36