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Showing 1–4 of 4 results
Advanced filters: Author: Mathias L. Heltberg Clear advanced filters

  • It is becoming clear that the dynamics of transcription factors may be important for gene regulation. Here, the authors study the implications of oscillatory and chaotic dynamics of NF-κB and demonstrate that it allows a degree of control of gene expression and can generate phenotypic heterogeneity.

    • Mathias L. Heltberg
    • Sandeep Krishna
    • Mogens H. Jensen
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-10

  • Circadian disruption can promote tumour formation. Now it is shown that the loss of circadian synchronization can drive this effect by disrupting the coupling between the circadian rhythm and the cell cycle within individual cells.

    • Nica Gutu
    • Malthe S. Nordentoft
    • Adrián E. Granada
    Research
    Nature Physics
    Volume: 21, P: 768-777

  • The mechanisms for regulating translation re-initiation in bacteria remain poorly understood. Here, the authors screened a library of synthetic operons and identified a ribosome termination structure that modulates re-initiation efficiency and which is conserved across bacteria.

    • Yonatan Chemla
    • Michael Peeri
    • Lital Alfonta
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-11

  • Synchronization can induce both order and disorder, betraying a multistability that is rife in living systems. Evidence now suggests that the circadian clock synchronizes with the cell cycle, and that this behaviour is common to different species.

    • Mathias L. Heltberg
    • Mogens H. Jensen
    News & Views
    Nature Physics
    Volume: 15, P: 989-990