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Showing 1–3 of 3 results
Advanced filters: Author: Mathieu Cayla Clear advanced filters

  • The African trypanosome Trypanosoma brucei has been shown to form stress granules in vitro that might be repurposed to enable differentiation and facilitate parasite transmission. Here, Cayla et al. show that differentiation between slender and stumpy forms does involve membrane-less granules that are different from nutritional stress granules.

    • Mathieu Cayla
    • Christos Spanos
    • Keith R. Matthews
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-16

  • Dendritic cells experience cell shape changes while migrating within the complex physical environment of tissues. Sensing of these shape changes modifies their migratory properties and imprints these cells with immunoregulatory properties.

    • Zahraa Alraies
    • Claudia A. Rivera
    • Ana-Maria Lennon-Duménil
    ResearchOpen Access
    Nature Immunology
    Volume: 25, P: 1193-1206

  • African trypanosomes can reduce their requirement for tsetse fly transmission, allowing an expanded geographical range. Here, molecular analyses of field and laboratory selected lines has identified adaptions for the parasite’s simplified life cycle.

    • Guy R. Oldrieve
    • Frank Venter
    • Keith R. Matthews
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-14