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Advanced filters: Author: Mathieu Tardat Clear advanced filters

  • The methyltransferase PR-Set7 catalyses the methylation of Histone H4 on Lys 20. This methylation mark is now found to correlate with replication-origin licensing. Expression of a non-degradable PR-Set7 mutant leads to retention of this mark and repeated DNA replication at origins.

    • Mathieu Tardat
    • Julien Brustel
    • Eric Julien
    Research
    Nature Cell Biology
    Volume: 12, P: 1086-1093