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Showing 1–4 of 4 results
Advanced filters: Author: Matias Ostrowski Clear advanced filters

  • A genome-wide study by the Long COVID Host Genetics Initiative identifies an association between the FOXP4 locus and long COVID, implicating altered lung function in its pathophysiology.

    • Vilma Lammi
    • Tomoko Nakanishi
    • Hanna M. Ollila
    ResearchOpen Access
    Nature Genetics
    Volume: 57, P: 1402-1417

  • Exosome biogenesis is poorly understood. The small GTPases Rab27a and Rab27b and their effectors, Slp4 and Slac2b, control exosome secretion at different steps by regulating the peripheral localization, retention and docking of exosomal precursors, the multivesicular endosomes.

    • Matias Ostrowski
    • Nuno B. Carmo
    • Clotilde Thery
    Research
    Nature Cell Biology
    Volume: 12, P: 19-30

  • Exosomes can act as messengers, carrying biological information between cells. Here, the authors describe the numerous effects that exosomes have on immune cells and discuss how they might be harnessed to promote or limit immune responses for therapeutic purposes.

    • Clotilde Théry
    • Matias Ostrowski
    • Elodie Segura
    Reviews
    Nature Reviews Immunology
    Volume: 9, P: 581-593