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Showing 1–2 of 2 results
Advanced filters: Author: Matilda Berkell Clear advanced filters

  • Here, the authors report the incidence of Clostridioides difficile infection (CDI) and assess potential clinical characteristics and biomarkers to predict CDI in 1,007 patients of 50 years and above receiving newly initiated antibiotic treatment.

    • Cornelis H. van Werkhoven
    • Annie Ducher
    • Odile Launay
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-10

  • Clostridioides difficile infection (CDI) is the most common cause of antibiotic-associated diarrhoea (AAD); however, markers predictive of CDI or AAD development are as yet lacking. Here, to identify markers predictive of CDI, the authors profile the intestinal microbiota of 945 hospitalised patients from 34 hospitals in 6 different European countries and show distinct microbiota enriched in Enterococcus and depleted of Ruminococcus, Blautia, Prevotella and Bifidobacterium compared to non-CDI patients.

    • Matilda Berkell
    • Mohamed Mysara
    • Odile Launay
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-14