Vitamin D has an important role in regulating the innate and adaptive immune response. Patients with kidney disease are often deficient in vitamin D, which could partly explain the high morbidity and mortality associated with infection that is commonly seen in these patients. In this Review, Sterling et al. describe the pleiotropic actions of vitamin D on the immune system and how vitamin D deficiency leads to immune dysfunction.
- Kevin A. Sterling
- Parham Eftekhari
- Dominic S. Raj
