Nature Search

Power-law behavior reveals phase transitions in landscape controls of fire regimes

Donald McKenzie
Maureen Kennedy
ResearchOpen Access10 Aug 2011
Nature Precedings

P: 1
Toll-like receptors TLR2 and TLR4 block the replication of pancreatic β cells in diet-induced obesity

High-energy diet triggers mild β cell proliferation to compensate for peripheral insulin resistance. Qi and colleagues show that TLR2 and TLR4 inhibit the diet-induced replication of β cells in mice and humans.

Yewei Ji
Shengyi Sun
Ling Qi
Research20 May 2019
Nature Immunology

Volume: 20, P: 677-686
Chalcone constituents pulincisones A-F isolated from Pulicaria incisa with NQO1 inducer activity

Ahmed R. Hamed
Tarik A. Mohamed
Mohamed-Elamir F. Hegazy
ResearchOpen Access20 Aug 2025
Scientific Reports

Volume: 15, P: 1-14
Mapping the human genetic architecture of COVID-19

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Mari E. K. Niemi
Juha Karjalainen
Chloe Donohue
ResearchOpen Access08 Jul 2021
Nature

Volume: 600, P: 472-477
GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

An analysis of 24,202 critical cases of COVID-19 identifies potentially druggable targets in inflammatory signalling (JAK1), monocyte–macrophage activation and endothelial permeability (PDE4A), immunometabolism (SLC2A5 and AK5), and host factors required for viral entry and replication (TMPRSS2 and RAB2A).

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
ResearchOpen Access17 May 2023
Nature

Volume: 617, P: 764-768
Whole-genome sequencing reveals host factors underlying critical COVID-19

Whole-genome sequencing, transcriptome-wide association and fine-mapping analyses in over 7,000 individuals with critical COVID-19 are used to identify 16 independent variants that are associated with severe illness in COVID-19.

Athanasios Kousathanas
Erola Pairo-Castineira
J. Kenneth Baillie
ResearchOpen Access07 Mar 2022
Nature

Volume: 607, P: 97-103
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
Development of selective bispecific Wnt mimetics for bone loss and repair

Antibody-based Wnt agonists are able to phenocopy Wnt signaling in vivo resulting in increased bone density, repair, and strength. Here, the authors show that Wnt agonists can reverse bone loss associated with ovariectomy and build stronger bone when administered after fracture.

Tristan W. Fowler
Troy L. Mitchell
Yang Li
ResearchOpen Access31 May 2021
Nature Communications

Volume: 12, P: 1-13
Antenatal Dexamethasone: Effect on Ovine Placental 11β-Hydroxysteroid Dehydrogenase Type 2 Expression and Fetal Growth

Leslie S Kerzner
Barbara S Stonestreet
Maureen P Malee
Research01 Nov 2002
Pediatric Research

Volume: 52, P: 706-712
Activation of diverse signalling pathways by oncogenic PIK3CA mutations

Mutations in PIK3CA, a catalytic subunit of PI3 kinase, are linked to deregulation of Akt-mTOR signalling in many cancers. Here, using a SILAC-based quantitative proteomic approach, the authors discover six new AKT1 substrates, including the actin regulator cortactin.

Xinyan Wu
Santosh Renuse
Akhilesh Pandey
Research23 Sept 2014
Nature Communications

Volume: 5, P: 1-13
Neonatal Meningitis in VLBW (<1.5 kg) Infants: Spinal Fluid Findings and Developmental Outcome at 20 Months

Benedict A Doctor
Nancy S Newman
Maureen Hack
Research01 Apr 1999
Pediatric Research

Volume: 45, P: 241
Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease

Openshaw and colleagues find myeloid inflammation and complement activation signatures in patients with long COVID who were previously hospitalized.

Felicity Liew
Claudia Efstathiou
J. Eunice Zhang
ResearchOpen Access08 Apr 2024
Nature Immunology

Volume: 25, P: 607-621
Whole-genome sequencing of patients with rare diseases in a national health system

Whole-genome sequencing and phenotype data sharing are introduced in a national health system to streamline diagnosis and to discover coding and non-coding variants that cause rare diseases.

Ernest Turro
William J. Astle
Willem H. Ouwehand
Research24 Jun 2020
Nature

Volume: 583, P: 96-102
Author Correction: GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
Amendments and CorrectionsOpen Access11 Jul 2023
Nature

Volume: 619, P: E61
A first update on mapping the human genetic architecture of COVID-19

Gita A. Pathak
Juha Karjalainen
J. Kenneth Baillie
ResearchOpen Access03 Aug 2022
Nature

Volume: 608, P: E1-E10
Timing of postnatal steroids for bronchopulmonary dysplasia: association with pulmonary and neurodevelopmental outcomes

Heidi M. Harmon
Erik A. Jensen
Elaine Romano
Research04 Feb 2020
Journal of Perinatology

Volume: 40, P: 616-627
Predicting breast cancer response to neoadjuvant chemotherapy using pretreatment diffuse optical spectroscopic texture analysis

William T Tran
Mehrdad J Gangeh
Gregory J Czarnota
ResearchOpen Access18 Apr 2017
British Journal of Cancer

Volume: 116, P: 1329-1339
Use of term reference infants in assessing the developmental outcome of extremely preterm infants: lessons learned in a multicenter study

Charles E. Green
Jon E. Tyson
Kimberlee Weaver-Lewis
ResearchOpen Access04 Aug 2023
Journal of Perinatology

Volume: 43, P: 1398-1405
A physiological role for connective tissue growth factor in early wound healing

Maria P Alfaro
Desirae L Deskins
Pampee P Young
Research19 Nov 2012
Laboratory Investigation

Volume: 93, P: 81-95
Ghrelin Increases GABAergic Transmission and Interacts with Ethanol Actions in the Rat Central Nucleus of the Amygdala

Maureen T Cruz
Melissa A Herman
Marisa Roberto
Research12 Sept 2012
Neuropsychopharmacology

Volume: 38, P: 364-375
Diverse capacity for 2-methylhopanoid production correlates with a specific ecological niche

Jessica N Ricci
Maureen L Coleman
Dianne K Newman
Research24 Oct 2013
The ISME Journal

Volume: 8, P: 675-684
Cortisol awakening response and developmental outcomes at 6–7 years in children born extremely preterm

Jean Lowe
Janell F. Fuller
Mary Johnson
Research17 Jun 2022
Pediatric Research

Volume: 93, P: 689-695

Search

Power-law behavior reveals phase transitions in landscape controls of fire regimes

Toll-like receptors TLR2 and TLR4 block the replication of pancreatic β cells in diet-induced obesity

Chalcone constituents pulincisones A-F isolated from Pulicaria incisa with NQO1 inducer activity

Mapping the human genetic architecture of COVID-19

GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

Whole-genome sequencing reveals host factors underlying critical COVID-19

A second update on mapping the human genetic architecture of COVID-19

Development of selective bispecific Wnt mimetics for bone loss and repair

Antenatal Dexamethasone: Effect on Ovine Placental 11β-Hydroxysteroid Dehydrogenase Type 2 Expression and Fetal Growth

Activation of diverse signalling pathways by oncogenic PIK3CA mutations

Neonatal Meningitis in VLBW (<1.5 kg) Infants: Spinal Fluid Findings and Developmental Outcome at 20 Months

Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease

Whole-genome sequencing of patients with rare diseases in a national health system

Author Correction: GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

A first update on mapping the human genetic architecture of COVID-19

Timing of postnatal steroids for bronchopulmonary dysplasia: association with pulmonary and neurodevelopmental outcomes

Predicting breast cancer response to neoadjuvant chemotherapy using pretreatment diffuse optical spectroscopic texture analysis

Use of term reference infants in assessing the developmental outcome of extremely preterm infants: lessons learned in a multicenter study

A physiological role for connective tissue growth factor in early wound healing

Ghrelin Increases GABAergic Transmission and Interacts with Ethanol Actions in the Rat Central Nucleus of the Amygdala

Diverse capacity for 2-methylhopanoid production correlates with a specific ecological niche

Cortisol awakening response and developmental outcomes at 6–7 years in children born extremely preterm

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