Mice engrafted with human cells are useful models for research on human malaria parasites. Here the authors show that the complete life cycle of Plasmodium falciparum and the liver stages of Plasmodium ovalecan be studied in mice doubly engrafted with human primary hepatocytes and red blood cells.
- Valérie Soulard
- Henriette Bosson-Vanga
- Dominique Mazier