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Showing 1–6 of 6 results
Advanced filters: Author: Max D. Wellenstein Clear advanced filters

  • Tripe-negative breast cancers poorly respond to immune checkpoint inhibition therapy, due to their immune-hostile tumour microenvironment. Authors here show that the oncogene MYC plays a pivotal role in suppressing anti-tumour immunity via directly regulating the transcription of interferon signalling genes.

    • Dario Zimmerli
    • Chiara S. Brambillasca
    • Jos Jonkers
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-18

  • Glucocorticoids (GC) are reported to block cancer cell proliferation, but the mode of action is unclear. Here the authors show that glucocorticoid receptor activation induces cancer cell dormancy in lung cancer by regulating CDKN1C expression through a distal enhancer, and these dormant cells are addicted to IGF-1R signalling pathway.

    • Stefan Prekovic
    • Karianne Schuurman
    • Wilbert Zwart
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-18

  • The measurement of the total cross-section of proton–proton collisions is of fundamental importance for particle physics. Here, the first measurement of the inelastic cross-section is presented for proton–proton collisions at an energy of 7 teraelectronvolts using the ATLAS detector at the Large Hadron Collider.

    • G. Aad
    • B. Abbott
    • L. Zwalinski
    ResearchOpen Access
    Nature Communications
    Volume: 2, P: 1-14

  • The traditionally held belief that neutrophils are inert bystanders in cancer has been challenged by the recent literature. This Review discusses the involvement of neutrophils in cancer initiation and progression, and their potential as biomarkers and therapeutic targets.

    • Seth B. Coffelt
    • Max D. Wellenstein
    • Karin E. de Visser
    Reviews
    Nature Reviews Cancer
    Volume: 16, P: 431-446